Interactive Guidance Therapy With Video Feed-back of Parent and Child With Autism Spectrum Disorder

NCT ID: NCT04607616

Last Updated: 2023-12-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

24 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-03-26

Study Completion Date

2026-01-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The purpose of this study is to assess the effect of Interactive Guidance Therapy with video feed back (IGT) of parent and child with Autism Spectrum Disorder, under three years of age, using a Single Case Experimental Design (SCED) with multiple baseline across subjects, multicentric, randomized, with multiple replications, blinded scored

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The purpose of this study is to assess the effect of Interactive Guidance Therapy with video feed back (IGT) of parent and child with Autism Spectrum Disorder, under three years of age, using a Single Case Experimental Design.

Early Interventions in Autism Spectrum Disorders (ASD) undergo a major development. The investigators identify three generations of early support: 1) Behavioral studies ; 2) Early Intensive Behavioral Interventions (EIBI), inspired by ABA, focused on targeted ASD disorders 3) Naturalistic Behavioral Developmental Behavioral Interventions (NDBI), more ecological, focused on the child's skills.

Among them, methods of video feedback target parental sensitivity (identification, interpretation, response, contingency and synchrony). The VIPP (Video Interactive Positive Parenting) in children less than one year of age, has shown moderate and long term effects on parent-child interaction. The PACT (Preschool Autism Communication Trial) showed immediate and in the long term effects on the synchronization of the parental response, the child initiation, less importantly on the joint attention, and on the autistic symptoms. The dyadic communication allows for changes in autistic symptoms.

Interactive guidance is a brief video-feedback therapy, based on the analysis of "the here and now" with the parent (s), of videotaped interactions with their child. The objective is to strengthen parental skills, their sensitivity, their ability to decipher and respond to the specific needs of their child.

The interest of IGT in the field of ASD, compared to VIPP and PACT, is to offer a standardized feedback intervention adapted to each dyad, according to the child's and parents skills and difficulties, structured on the "here and now" more than on a predetermined sequence of goals.

The investigators use the Single Case Experimental Design (SCED) with multiple baseline across subjects, multicentric, randomized, with multiple replications, blinded scored.

They expect

* to improve the interactive and communicative basic skills of the child, soon after the ASD diagnosis, by accompanying the parents in the identification and understanding of their child's disorders.
* to propose a method highlighting parental skills, in a collaborative and pleasant way
* To increase the parental alliance in the implementation of a tailored intervention for the child
* To facilitate access to healthcare and reduce the parental wandering in the implementation of intervention

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Autism Spectrum Disorders

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

Autism Spectrum Disorders Interactive guidance therapy Video feed-back

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

3 baselines sessions Treatment As Usual (TAU)

Patients received 3 baseline sessions before interactive guidance therapy

Group Type EXPERIMENTAL

Baseline sessions TAU

Intervention Type BEHAVIORAL

TAU consists of sessions lasting around one/one and a half hour ; the consultant is practicing as usual. The interventions focus on child's behavior, parent infant relationship, with moments of play with the child, advices, informations about child development and Autism.

Interactive guidance therapy

Intervention Type BEHAVIORAL

The objective is to reinforce the identification, deciphering, interpretation, and answer to child's signals by the parent, in order to to promote a synchronous and attuned response to the child's needs.

Sessions last around one/one and a half hour. Parent plays 7-10 minutes with the child, in the presence of the therapist, with toys chosen according to the child's developmental stage. Then therapist proposes an immediate viewing of the play session. The therapist selects short moments of positive interaction. He has determined a " focus ", depending on the play, previous sessions, the child's difficulties and parent's interventions. He accompanies, guides and supports the parent to describe the interaction, the alternance in play, joint attention, shared affect, in a co-construction: the parent discovers the child's and his own skills.

Developmental and diagnostic assessments

Intervention Type DIAGNOSTIC_TEST

MSEL, CARS, ECAR, CIM10, DMS5, ADOS, ADIR

Developmental assessment -Parental scales

Intervention Type BEHAVIORAL

Vineland II, IFDC, IDE

Qualitative analysis

Intervention Type BEHAVIORAL

Interpretative Phenomenological Analysis. Parents' semi structured interview about the Interactive Guidance experience. Qualitative analysis of transcripts (recurrent themes, meta themes).

4 baselines sessions TAU

Patients received 4 baseline sessions before interactive guidance therapy

Group Type EXPERIMENTAL

Baseline sessions TAU

Intervention Type BEHAVIORAL

TAU consists of sessions lasting around one/one and a half hour ; the consultant is practicing as usual. The interventions focus on child's behavior, parent infant relationship, with moments of play with the child, advices, informations about child development and Autism.

Interactive guidance therapy

Intervention Type BEHAVIORAL

The objective is to reinforce the identification, deciphering, interpretation, and answer to child's signals by the parent, in order to to promote a synchronous and attuned response to the child's needs.

Sessions last around one/one and a half hour. Parent plays 7-10 minutes with the child, in the presence of the therapist, with toys chosen according to the child's developmental stage. Then therapist proposes an immediate viewing of the play session. The therapist selects short moments of positive interaction. He has determined a " focus ", depending on the play, previous sessions, the child's difficulties and parent's interventions. He accompanies, guides and supports the parent to describe the interaction, the alternance in play, joint attention, shared affect, in a co-construction: the parent discovers the child's and his own skills.

Developmental and diagnostic assessments

Intervention Type DIAGNOSTIC_TEST

MSEL, CARS, ECAR, CIM10, DMS5, ADOS, ADIR

Developmental assessment -Parental scales

Intervention Type BEHAVIORAL

Vineland II, IFDC, IDE

Qualitative analysis

Intervention Type BEHAVIORAL

Interpretative Phenomenological Analysis. Parents' semi structured interview about the Interactive Guidance experience. Qualitative analysis of transcripts (recurrent themes, meta themes).

5 baselines sessions TAU

Patients received 5 baseline sessions before interactive guidance therapy

Group Type EXPERIMENTAL

Baseline sessions TAU

Intervention Type BEHAVIORAL

TAU consists of sessions lasting around one/one and a half hour ; the consultant is practicing as usual. The interventions focus on child's behavior, parent infant relationship, with moments of play with the child, advices, informations about child development and Autism.

Interactive guidance therapy

Intervention Type BEHAVIORAL

The objective is to reinforce the identification, deciphering, interpretation, and answer to child's signals by the parent, in order to to promote a synchronous and attuned response to the child's needs.

Sessions last around one/one and a half hour. Parent plays 7-10 minutes with the child, in the presence of the therapist, with toys chosen according to the child's developmental stage. Then therapist proposes an immediate viewing of the play session. The therapist selects short moments of positive interaction. He has determined a " focus ", depending on the play, previous sessions, the child's difficulties and parent's interventions. He accompanies, guides and supports the parent to describe the interaction, the alternance in play, joint attention, shared affect, in a co-construction: the parent discovers the child's and his own skills.

Developmental and diagnostic assessments

Intervention Type DIAGNOSTIC_TEST

MSEL, CARS, ECAR, CIM10, DMS5, ADOS, ADIR

Developmental assessment -Parental scales

Intervention Type BEHAVIORAL

Vineland II, IFDC, IDE

Qualitative analysis

Intervention Type BEHAVIORAL

Interpretative Phenomenological Analysis. Parents' semi structured interview about the Interactive Guidance experience. Qualitative analysis of transcripts (recurrent themes, meta themes).

6 baselines sessions TAU

Patients received 6 baseline sessions before interactive guidance therapy

Group Type EXPERIMENTAL

Baseline sessions TAU

Intervention Type BEHAVIORAL

TAU consists of sessions lasting around one/one and a half hour ; the consultant is practicing as usual. The interventions focus on child's behavior, parent infant relationship, with moments of play with the child, advices, informations about child development and Autism.

Interactive guidance therapy

Intervention Type BEHAVIORAL

The objective is to reinforce the identification, deciphering, interpretation, and answer to child's signals by the parent, in order to to promote a synchronous and attuned response to the child's needs.

Sessions last around one/one and a half hour. Parent plays 7-10 minutes with the child, in the presence of the therapist, with toys chosen according to the child's developmental stage. Then therapist proposes an immediate viewing of the play session. The therapist selects short moments of positive interaction. He has determined a " focus ", depending on the play, previous sessions, the child's difficulties and parent's interventions. He accompanies, guides and supports the parent to describe the interaction, the alternance in play, joint attention, shared affect, in a co-construction: the parent discovers the child's and his own skills.

Developmental and diagnostic assessments

Intervention Type DIAGNOSTIC_TEST

MSEL, CARS, ECAR, CIM10, DMS5, ADOS, ADIR

Developmental assessment -Parental scales

Intervention Type BEHAVIORAL

Vineland II, IFDC, IDE

Qualitative analysis

Intervention Type BEHAVIORAL

Interpretative Phenomenological Analysis. Parents' semi structured interview about the Interactive Guidance experience. Qualitative analysis of transcripts (recurrent themes, meta themes).

7 baselines sessions TAU

Patients received 7 baseline sessions before interactive guidance therapy

Group Type EXPERIMENTAL

Baseline sessions TAU

Intervention Type BEHAVIORAL

TAU consists of sessions lasting around one/one and a half hour ; the consultant is practicing as usual. The interventions focus on child's behavior, parent infant relationship, with moments of play with the child, advices, informations about child development and Autism.

Interactive guidance therapy

Intervention Type BEHAVIORAL

The objective is to reinforce the identification, deciphering, interpretation, and answer to child's signals by the parent, in order to to promote a synchronous and attuned response to the child's needs.

Sessions last around one/one and a half hour. Parent plays 7-10 minutes with the child, in the presence of the therapist, with toys chosen according to the child's developmental stage. Then therapist proposes an immediate viewing of the play session. The therapist selects short moments of positive interaction. He has determined a " focus ", depending on the play, previous sessions, the child's difficulties and parent's interventions. He accompanies, guides and supports the parent to describe the interaction, the alternance in play, joint attention, shared affect, in a co-construction: the parent discovers the child's and his own skills.

Developmental and diagnostic assessments

Intervention Type DIAGNOSTIC_TEST

MSEL, CARS, ECAR, CIM10, DMS5, ADOS, ADIR

Developmental assessment -Parental scales

Intervention Type BEHAVIORAL

Vineland II, IFDC, IDE

Qualitative analysis

Intervention Type BEHAVIORAL

Interpretative Phenomenological Analysis. Parents' semi structured interview about the Interactive Guidance experience. Qualitative analysis of transcripts (recurrent themes, meta themes).

8 baselines sessions TAU

Patients received 8 baseline sessions before interactive guidance therapy

Group Type EXPERIMENTAL

Baseline sessions TAU

Intervention Type BEHAVIORAL

TAU consists of sessions lasting around one/one and a half hour ; the consultant is practicing as usual. The interventions focus on child's behavior, parent infant relationship, with moments of play with the child, advices, informations about child development and Autism.

Interactive guidance therapy

Intervention Type BEHAVIORAL

The objective is to reinforce the identification, deciphering, interpretation, and answer to child's signals by the parent, in order to to promote a synchronous and attuned response to the child's needs.

Sessions last around one/one and a half hour. Parent plays 7-10 minutes with the child, in the presence of the therapist, with toys chosen according to the child's developmental stage. Then therapist proposes an immediate viewing of the play session. The therapist selects short moments of positive interaction. He has determined a " focus ", depending on the play, previous sessions, the child's difficulties and parent's interventions. He accompanies, guides and supports the parent to describe the interaction, the alternance in play, joint attention, shared affect, in a co-construction: the parent discovers the child's and his own skills.

Developmental and diagnostic assessments

Intervention Type DIAGNOSTIC_TEST

MSEL, CARS, ECAR, CIM10, DMS5, ADOS, ADIR

Developmental assessment -Parental scales

Intervention Type BEHAVIORAL

Vineland II, IFDC, IDE

Qualitative analysis

Intervention Type BEHAVIORAL

Interpretative Phenomenological Analysis. Parents' semi structured interview about the Interactive Guidance experience. Qualitative analysis of transcripts (recurrent themes, meta themes).

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Baseline sessions TAU

TAU consists of sessions lasting around one/one and a half hour ; the consultant is practicing as usual. The interventions focus on child's behavior, parent infant relationship, with moments of play with the child, advices, informations about child development and Autism.

Intervention Type BEHAVIORAL

Interactive guidance therapy

The objective is to reinforce the identification, deciphering, interpretation, and answer to child's signals by the parent, in order to to promote a synchronous and attuned response to the child's needs.

Sessions last around one/one and a half hour. Parent plays 7-10 minutes with the child, in the presence of the therapist, with toys chosen according to the child's developmental stage. Then therapist proposes an immediate viewing of the play session. The therapist selects short moments of positive interaction. He has determined a " focus ", depending on the play, previous sessions, the child's difficulties and parent's interventions. He accompanies, guides and supports the parent to describe the interaction, the alternance in play, joint attention, shared affect, in a co-construction: the parent discovers the child's and his own skills.

Intervention Type BEHAVIORAL

Developmental and diagnostic assessments

MSEL, CARS, ECAR, CIM10, DMS5, ADOS, ADIR

Intervention Type DIAGNOSTIC_TEST

Developmental assessment -Parental scales

Vineland II, IFDC, IDE

Intervention Type BEHAVIORAL

Qualitative analysis

Interpretative Phenomenological Analysis. Parents' semi structured interview about the Interactive Guidance experience. Qualitative analysis of transcripts (recurrent themes, meta themes).

Intervention Type BEHAVIORAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* 18 months to 3 years child at screening
* Child with a diagnosis of Autism Spectrum Disorder (DSM 5) or pervasive Developmental Disorder (ICD 10)
* Child with ADI R and ADOS-2 fulfilling the criteria for TSA / PDD at diagnosis
* Developmental age \> 12 months in motility with the Brunet-Lézine test
* Child with availability of parent most present in daily life, only this parent participating directly in play sessions
* Signed Informed consent form by both parents
* Patient affiliated to the health insurance system

Exclusion Criteria

* Level of language in French of parents insufficient to benefit from the care and fill in the questionnaires
* Psychiatric parental pathology interfering with interactions with the child, qualitatively assessed by the referring psychiatrist
* Severe sensory illness of the child (blindness, deafness, degenerative disease)
Minimum Eligible Age

18 Months

Maximum Eligible Age

3 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Ville Evrard Hospital

UNKNOWN

Sponsor Role collaborator

Assistance Publique - Hôpitaux de Paris

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Benoit QUIROT, MD

Role: STUDY_DIRECTOR

EPS Ville Evrard

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Hôpital Saint Eloi

Montpellier, , France

Site Status RECRUITING

Hôpital Ville Evrard

Montreuil, , France

Site Status RECRUITING

Hôpital Pitié Salpétriere

Paris, , France

Site Status RECRUITING

Hôpital Necker Enfants Malades

Paris, , France

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

France

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Lisa OUSS, MD

Role: CONTACT

Phone: +33 1 44 49 45 61

Email: [email protected]

Laure CHOUPEAUX, Master

Role: CONTACT

Phone: +33 1 44 38 17 11

Email: [email protected]

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Marie-joelle HERVE, MD

Role: primary

Benoit QUIROT, MD

Role: primary

Sylvie VIAUX, MD

Role: primary

lisa OUSS, MD

Role: primary

References

Explore related publications, articles, or registry entries linked to this study.

1. McDonough S. Interaction guidance. Treat Parent-infant Relatsh Probl Strateg Interv. 2004;79-96.

Reference Type BACKGROUND

2. McDonough SC. Promoting positive early parent-infant relationships through interaction guidance. Child Adolesc Psychiatr Clin N Am. 1995;4(3):661-72.

Reference Type BACKGROUND

Rusconi-Serpa S, Sancho Rossignol A, McDonough SC. Video feedback in parent-infant treatments. Child Adolesc Psychiatr Clin N Am. 2009 Jul;18(3):735-51. doi: 10.1016/j.chc.2009.02.009.

Reference Type BACKGROUND
PMID: 19486848 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

2019-A02707-50

Identifier Type: OTHER

Identifier Source: secondary_id

APHP180671

Identifier Type: -

Identifier Source: org_study_id