Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
56 participants
OBSERVATIONAL
2021-01-18
2022-05-17
Brief Summary
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The main objective is to evaluate the association of exercise lung ultrasound data acquired during a stress test on a bicycle ergometer with the diagnosis of heart failure with preserved ejection fraction (HFpEF).
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Detailed Description
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1. To assess the diagnostic performance of exercise lung ultrasound for the diagnosis of HFpEF.
2. To identify the value of the B-lines score on exercise maximizing the sensitivity and specificity for the diagnosis of HFpEF.
3. To evaluate the relationship of the delta of B-lines scores between rest and exercise with the diagnosis of HFpEF.
4. To assess the diagnostic performance of the delta of B-lines between rest and exercise for the diagnosis of HFpEF.
5. To identify the score of the delta of B-lines value between rest and exercise maximizing sensitivity and specificity for the diagnosis of HFpEF.
6. To evaluate the relationship between the resting value of the B-lines scores with the diagnosis of HFpEF.
7. To assess the diagnostic performance of the resting lung ultrasound for the diagnosis of HFpEF.
8. To identify the value of the B-lines score at rest maximizing the sensitivity and specificity for the diagnosis of HFpEF.
9. To evaluate the correlation between the B-line score measured at rest and exercise and the dyspnoea score measured at rest, during exercise, and during the recovery phase.
10. To assess the correlation of the delta of B-lines scores between rest and exercise and the dyspnoea score measured at rest, during exercise and during the recovery phase.
Conditions
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Study Design
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CASE_CONTROL
PROSPECTIVE
Study Groups
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Case group: patients with heart failure with preserved ejection fraction
Lung ultrasound
A lung ultrasound before and at the end of the stress test.
Control Group:Never diagnosed with either preserved or altered ejection fraction heart failure.
Non dyspnoeic patients with no history of Heart failure.
Lung ultrasound
A lung ultrasound before and at the end of the stress test.
Interventions
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Lung ultrasound
A lung ultrasound before and at the end of the stress test.
Eligibility Criteria
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Inclusion Criteria
* Never diagnosed with either preserved or altered ejection fraction heart failure
* Non-dyspneic (New York Heart Association class I)
* Patients 65 years of age and older scheduled for a stress test.
* Patients already diagnosed with HFpEF following hospitalization for heart failure (LVEF\>50%)
Exclusion Criteria
* Pulmonary or pleural pathology preventing reliable acquisition of lung ultrasound images (e.g. pulmonary fibrosis, diffuse interstitial lung disease or lung cancer)
* Patients with a history of thoracic surgery
* Patients under legal protection measures (guardianship, curator, judicial safeguard),
* Pregnant women, parturient women or nursing mothers,
* Patients who are unable to express consent,
* Persons deprived of their liberty by a judicial or administrative decision,
* Persons subject to psychiatric care,
* Patients discharged from hospital for a worsening heart failure hospitalization for less than 15 days
65 Years
ALL
Yes
Sponsors
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Central Hospital, Nancy, France
OTHER
Responsible Party
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Mathieu ECHIVARD
Praticien hospitalier
Locations
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CHRU de Nancy
Vandœuvre-lès-Nancy, , France
Countries
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Other Identifiers
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2020PI156
Identifier Type: -
Identifier Source: org_study_id
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