End-range Mobilization on Time Curve of Pressure Pain Threshold
NCT ID: NCT04629625
Last Updated: 2022-09-08
Study Results
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Basic Information
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COMPLETED
NA
66 participants
INTERVENTIONAL
2020-10-10
2021-05-01
Brief Summary
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Detailed Description
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The different joint-based mobilization techniques may not only alleviate pain, but also increase pain tolerance to the locally applied mechanical pressure. Positive results of these techniques on increase of PPT has been reported in knee OA; however, the time curve of PPT has not evaluated so far in knee OA. Therefore, the aim of this study was to investigate the effect of end-range mobilization on the time curve of PPT and some function-related measures in knee OA.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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End-range mobilization
End-range mobilization performed in end-position of the tibiofemoral joints' flexion and extension for 2\*3 min
End-range mobilization
End-range mobilization performed in end-range of the tibiofemoral joints' flexion and extension
Non end-range mobilization
Non end-range mobilization performed in tibiofemoral joints' loose position
Non end-range mobilization
Non end-range mobilization performed in tibiofemoral joints' loose position
Placebo
Hands-on treatment technique performed in end-range of the tibiofemoral joints' flexion and extension for 2\*3 min
Placebo
Hands-on technique performed in end-range of the tibiofemoral joints' flexion and extension
Interventions
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End-range mobilization
End-range mobilization performed in end-range of the tibiofemoral joints' flexion and extension
Non end-range mobilization
Non end-range mobilization performed in tibiofemoral joints' loose position
Placebo
Hands-on technique performed in end-range of the tibiofemoral joints' flexion and extension
Eligibility Criteria
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Inclusion Criteria
* Categorization of patients as End Of Range Problem based on manual therapy
* unilateral/bilateral symptomatic tibiofemoral knee osteoarthritis with radiographic evidence of Kellgren-Lawrence scale between 1 and 3
* pain during weight-bearing activities at least within 6 months
* sufficient mental status
Exclusion Criteria
* class II. obesity (body mass index, BMI\>35kg/m2)
* severe degenerative lumbar spine disease (e.g. spondylolisthesis)
* systemic inflammatory arthritic or neurological condition
* physiotherapy/balneotherapy attendance or manual therapy within 3 months
* intraarticular injections in the prior 12 months
* use of walking aids
* contraindication for manual therapy
* complex regional pain syndrome
* cognitive impairment
60 Years
80 Years
ALL
No
Sponsors
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University of Pecs
OTHER
Responsible Party
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Principal Investigators
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Miklós Pozsgai
Role: STUDY_CHAIR
Harkány Thermal Rehabilitation Centre
Locations
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Harkány Thermal Rehabilitation Centre
Harkány, Please Select, Hungary
Miklós Pozsgai
Harkány, Please Select, Hungary
Countries
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References
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Kidd BL. Osteoarthritis and joint pain. Pain. 2006 Jul;123(1-2):6-9. doi: 10.1016/j.pain.2006.04.009. Epub 2006 May 22. No abstract available.
Wise BL, Niu J, Zhang Y, Wang N, Jordan JM, Choy E, Hunter DJ. Psychological factors and their relation to osteoarthritis pain. Osteoarthritis Cartilage. 2010 Jul;18(7):883-7. doi: 10.1016/j.joca.2009.11.016. Epub 2010 Mar 24.
Bajaj P, Bajaj P, Graven-Nielsen T, Arendt-Nielsen L. Osteoarthritis and its association with muscle hyperalgesia: an experimental controlled study. Pain. 2001 Aug;93(2):107-114. doi: 10.1016/S0304-3959(01)00300-1.
Imamura M, Imamura ST, Kaziyama HH, Targino RA, Hsing WT, de Souza LP, Cutait MM, Fregni F, Camanho GL. Impact of nervous system hyperalgesia on pain, disability, and quality of life in patients with knee osteoarthritis: a controlled analysis. Arthritis Rheum. 2008 Oct 15;59(10):1424-31. doi: 10.1002/art.24120.
Wylde V, Palmer S, Learmonth ID, Dieppe P. Somatosensory abnormalities in knee OA. Rheumatology (Oxford). 2012 Mar;51(3):535-43. doi: 10.1093/rheumatology/ker343. Epub 2011 Nov 24.
Hendiani JA, Westlund KN, Lawand N, Goel N, Lisse J, McNearney T. Mechanical sensation and pain thresholds in patients with chronic arthropathies. J Pain. 2003 May;4(4):203-11. doi: 10.1016/s1526-5900(03)00557-1.
Kaya Mutlu E, Ercin E, Razak Ozdincler A, Ones N. A comparison of two manual physical therapy approaches and electrotherapy modalities for patients with knee osteoarthritis: A randomized three arm clinical trial. Physiother Theory Pract. 2018 Aug;34(8):600-612. doi: 10.1080/09593985.2018.1423591. Epub 2018 Jan 8.
Khademi-Kalantari K, Mahmoodi Aghdam S, Akbarzadeh Baghban A, Rezayi M, Rahimi A, Naimee S. Effects of non-surgical joint distraction in the treatment of severe knee osteoarthritis. J Bodyw Mov Ther. 2014 Oct;18(4):533-9. doi: 10.1016/j.jbmt.2013.12.001. Epub 2013 Dec 11.
Other Identifiers
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MaitlandKneePPT_Time Curve
Identifier Type: -
Identifier Source: org_study_id
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