Treatment of Complex Regional Pain Syndrome, a Long-term Follow-up

NCT ID: NCT04597866

Last Updated: 2024-02-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

10 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-09-21

Study Completion Date

2021-12-31

Brief Summary

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Complex regional pain syndrome, CRPS, is an uncommon but often very disabling chronic pain syndrome characterized by, beside pain: sensory disturbances, peripheral autonomic changes and inflammatory features. The diagnosis is subdivided in CRPS type 1 where no nerve injury has been identified, and CRPS type 2 when a major nerve injury has been verified.

A combination of exposure in vivo, a form of behaviour therapy where the patient is gradually confronted with avoided movements and activities, and interventions directly targeting a hypothesized cortical reorganisation is an interesting novel approach for treating CRPS.

The present study consists of (1) a qualitative interview study with 10-15 subjects that has received this form of treatment, in order to better understand their experience and effects of the treatment, and (2) a case series with long-term follow-up of 3-5 subjects that received the treatment för 5-8 years ago, in order to study the long term effects of the treatment.

Detailed Description

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Conditions

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Complex Regional Pain Syndromes Chronic Pain

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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CRPS

Multimodal rehabilitation

Intervention Type BEHAVIORAL

A combination of exposure in vivo and interventions directly targeting the cortical reorganization for treating CRPS.

Interventions

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Multimodal rehabilitation

A combination of exposure in vivo and interventions directly targeting the cortical reorganization for treating CRPS.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Has participated in multimodal treatment for CRPS at Uppsala University Hospital

Exclusion Criteria

* Other serious physical or mental condition
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Uppsala University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Kristoffer Bothelius, PhD

Role: PRINCIPAL_INVESTIGATOR

Uppsala University

Locations

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Uppsala University

Uppsala, , Sweden

Site Status

Countries

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Sweden

Other Identifiers

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2020-03383

Identifier Type: -

Identifier Source: org_study_id

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