Effect of Corticosteroid Treatment on Prognosis in ARDS Secondary to Covid-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-03-01

Study Completion Date

2020-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Study conducted on hospitalized patient in critical ill units in Nancy and Metz to evaluate if early corticosteroid treatment in first seven days after admission improve patients outcome in Acute Respiratory Distress Syndrome secondary to Covid-19 compared to later corticosteroid therapy or no treatment. Also comparison of acquired infection with or without corticosteroid treatment during hospitalisation.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Comparison of ARDS COVID-19 (WHO) vs ARDS Influenza in the ICU

NCT04941092

ARDS COVID-19 Acute Respiratory Distress Syndrome Influenza

COMPLETED

High-dose, Short-term Steroid and Low-dose Long-term Steroid Use in ARDS Caused by COVID-19

NCT05047874

Short-term (3 Days) High-dose (1000 mg) Systemic Methylprednisolone

UNKNOWN

PREdiction of DIagnosed Covid-19 infecTion in IUC Patients

NCT04327180

Infection Viral Coronavirus ARDS +1 more

COMPLETED

Coronavirus Studied by Metagenomics in ARDS COVID-19 Patients

NCT04516486

Respiratory Distress Syndrome, Adult COVID-19

UNKNOWN

Consequences in ICU of Vaccination Status of Covid-19 Patients

NCT06191341

SARS CoV 2 Infection

COMPLETED

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Acute Respiratory Distress Syndrome Secondary to Covid-19

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Early corticosteroid

Corticosteroid treatment within first seven days after ICU admission

Corticosteroids and Derivatives

Intervention Type DRUG

Any systemic corticosteroid treatment administrated during ICU stay

Late corticosteroid

Corticosteroid treatment later than seventh day's after ICU admission

Corticosteroids and Derivatives

Intervention Type DRUG

Any systemic corticosteroid treatment administrated during ICU stay

No corticosteroid

No corticosteroid treatment during ICU stay

No interventions assigned to this group

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Corticosteroids and Derivatives

Any systemic corticosteroid treatment administrated during ICU stay

Intervention Type DRUG

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* ICU hospitalized with acute respiratory distress syndrome secondary to Sars-Cov-2 infection diagnosed by PCR test
* Hospitalized from 01/03/2020 to 30/04/2020

Exclusion Criteria

* Mechanical ventilation more than 48 hours at admission
* Transfert to another ICU during stay for bed management
* Corticosteroid treatment at admission

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No