MagnezixKids Study

NCT ID: NCT04571905

Last Updated: 2023-09-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

17 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-08-01

Study Completion Date

2023-07-12

Brief Summary

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The overall objective of the study is to describe the outcomes of osteosyn-thesis with magnesium based screws in children with a primary or second-ary (within 7 days from trauma) dislocated fracture of the Epicondyles ul-naris or Condylus radialis, and to compare them with outcomes of conven-tional osteosynthesis using steel screws.

If our results suggest non-inferiority of osteosynthesis with magnesium-based screws, the procedure could be tested formally in a subsequent full-size study.

Detailed Description

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Conditions

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Magnesium-based Bioresrobable Implants Pediatric Elbow Fractures Osteosynthesis Childhood Magnezix Elbow Fracture

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Syntellix Treatment Arm

General anaesthesia, open fracture reduction, insertion of the appropriate screw with x-ray control and documentation intraoperatively, cast immobilisation Use of bioresorbable Magnezix CS or CBS Screws, if intraoperatively suitable bioresorbable screws not available, use of conventional ostesynthesis screws

Group Type OTHER

Osteosynthesis with resorbable Material

Intervention Type DEVICE

Osteosynthesis with Magnezix screws in fractures of the Epicondylus ulnaris and Condylus radialis under General anaesthesia

Interventions

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Osteosynthesis with resorbable Material

Osteosynthesis with Magnezix screws in fractures of the Epicondylus ulnaris and Condylus radialis under General anaesthesia

Intervention Type DEVICE

Other Intervention Names

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Magnezix (Syntellix) screws

Eligibility Criteria

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Inclusion Criteria

* primary or secondary (within 7 days from trauma) dislocated fracture of the Epicondyles ulnaris or Condylus radialis (indication for operative treatment according to international standard: Dislocation of more than 2 mm in Condylus radials fractures and more than 5 mm in Epicondylus ulnas fractures )
* Age 3-15 years
* Informed Consent as documented by signature

Exclusion Criteria

* \- open fractures or complex multi fragment fractures that require dif-ferent osteosynthetic procedures than screw fixation
* severe local accompanying injury (injury to nerves/vessels)
* polytrauma patients
* fracture age \> 7 days
* preexisting ipsilateral elbow fracture
* relevant comorbidities, which have influence on fracture and wound healing
* Inability to follow the procedures of the study, e.g. due to language problems, psychological disorders, dementia, etc. of the participant or the legal representatives
* Previous enrolment into the current study
* Enrolment of the investigator's family members and other dependent persons
* Any of the following applicable absolute and relative contraindica-tions listed in the MAGNEZIX® CBS and CSc 4.8 mm instruction for use :

Absolute contraindications:

* insufficient or avascular bone mass for anchorage of the implant, ex-cept osteochondral fractures and dissecates
* confirmation or suspected septic infectious surgical site
* application in the area of the epiphyseal plates

Relative contraindications:

* acute sepsis
* alcohol, nicotine and/or drug abuse
* epilepsy
* poor skin/soft tissue conditions
* uncooperative patient or patient with restricted intellectual capacity
* no options for adequate postoperative treatment (e.g. temporary strain relief)
Minimum Eligible Age

3 Years

Maximum Eligible Age

15 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Thomas Krebs

OTHER

Sponsor Role lead

Responsible Party

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Thomas Krebs

Surgeon in Chief, Member of the executive board

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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Childres Hospital of Eastern Switzerland

Sankt Gallen, , Switzerland

Site Status

Countries

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Switzerland

Other Identifiers

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CTU 18.028

Identifier Type: -

Identifier Source: org_study_id

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