Impact of Pre-procedure Cognitive Status on Outcome at 3 Months After Transcatheter Aortic Valve Implantation

NCT ID: NCT04564534

Last Updated: 2022-02-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

109 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-10-09

Study Completion Date

2021-09-30

Brief Summary

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This study plans to investigate the relationship between cognitive status pre-procedure, and clinical outcomes at 3 months in patients undergoing transcatheter aortic valve implantation (TAVI).

Detailed Description

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This study plans to investigate the relationship between cognitive status pre-procedure, as assessed using the Montreal Cognitive Assessment (MoCA) administered on a tablet, and clinical outcomes at 3 months as assessed by the VARC2 criteria, in patients undergoing transcatheter aortic valve implantation (TAVI)

Conditions

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Aortic Stenosis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Study cohort

Adult (\>18 years) patients with aortic stenosis in whom TAVI is planned and who perform their pre-TAVI work-up in our centre will be invited to undergo cognitive assessment using the MoCA at the time of their hospitalization for pre-TAVI work-up.

The MoCA will be administered by trained professionals with MoCA certification.

Clinical outcomes, as assessed by the VARC2 criteria, will be collected for all patients at 3 months after the TAVI procedure.

MoCA cognitive assessment

Intervention Type OTHER

cognitive assessment using the validated MoCA test administered via an application on an iPad

Interventions

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MoCA cognitive assessment

cognitive assessment using the validated MoCA test administered via an application on an iPad

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Aged 18 years or over
* Scheduled to undergo TAVI
* Provide informed consent
* Able to understand French

Exclusion Criteria

* subjects under legal guardianship or other legal protection
* subjects with documented severe dementia
* subjects with anticipated poor compliance
* subjects unable to understand French sufficiently well to perform the MoCA test
* pregnant women
* subjects within the exclusion period of another study
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Universitaire de Besancon

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Francois Schiele, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

CHRU Besancon

Locations

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University Hospital Jean Minjoz

Besançon, , France

Site Status

Countries

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France

Other Identifiers

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P/2019/417

Identifier Type: -

Identifier Source: org_study_id

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