Effects of a Face Mask on Oxygenation During Exercise

NCT ID: NCT04557605

Last Updated: 2020-10-20

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 14 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2020-09-14
• Study Completion Date: 2020-10-15

Brief Summary

There is concern that wearing a face mask during COVID will affect oxygen uptake, especially during intense exercise. This study will assess the effect of wearing two different face masks (disposable and cloth) on blood and muscle oxygenation during cycling exercise.

Detailed Description

There is concern that wearing a face mask during exercise will reduce oxygen uptake or increase carbon dioxide re-breathing, which can result in low blood oxygen levels, reduced oxygen delivery to muscle and reduced exercise capacity. The purpose of the study is to determine the effect of wearing two different types of commonly-worn face masks (diposable and cloth) during exercise on blood and muscle oxygenation. Twelve participants who are experienced with cycling will take part in this randomized cross-over study that will assess blood oxygenation (i.e. pulse oximetry) and muscle oxygenation (with near infrared spectroscopy) during a progressive step exercise test to exhaustion. The conditions include no mask, a disposable mask, and a cloth mask. Outcome variables include exercise duration, rating of perceived exertion, blood oxygen saturation levels, and oxygenated, deoxygenated, and total hemoglobin at the quadriceps muscle.

Conditions

Hypoxemia

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: CROSSOVER
• Primary Study Purpose: TREATMENT
• Blinding Strategy: SINGLE

Study Groups

No face mask

Progressive step-exercise cycling test to exhaustion wearing no face mask

Group Type: ACTIVE_COMPARATOR

Progressive cycling exercise test to exhaustion

Intervention Type: OTHER

Progressive step cycling exercise test to exhaustion

Disposable face mask

Progressive step-exercise cycling test to exhaustion wearing a 3-ply disposable face mask

Group Type: EXPERIMENTAL

Progressive cycling exercise test to exhaustion

Intervention Type: OTHER

Progressive step cycling exercise test to exhaustion

Cloth face mask

Progressive step-exercise cycling test to exhaustion wearing a cloth face mask

Group Type: EXPERIMENTAL

Progressive cycling exercise test to exhaustion

Intervention Type: OTHER

Progressive step cycling exercise test to exhaustion

Interventions

Progressive cycling exercise test to exhaustion

Progressive step cycling exercise test to exhaustion

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Experienced with cycling

Exclusion Criteria

• Contra-indications to exercise as identified by a screening questionnaire (the "Get Active Questionnaire")

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

University of Saskatchewan

OTHER

Sponsor Role: lead

Responsible Party

Phil Chilibeck

Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Philip Chilibeck, Ph.D.

Role: PRINCIPAL_INVESTIGATOR

University of Saskatchewan

Locations

University of Saskatchewan

Saskatoon, Saskatchewan, Canada

Countries

Canada

References

Shaw K, Butcher S, Ko J, Zello GA, Chilibeck PD. Wearing of Cloth or Disposable Surgical Face Masks has no Effect on Vigorous Exercise Performance in Healthy Individuals. Int J Environ Res Public Health. 2020 Nov 3;17(21):8110. doi: 10.3390/ijerph17218110.

Reference Type: DERIVED

PMID: 33153145 (View on PubMed)

Other Identifiers

2201

Identifier Type: -

Identifier Source: org_study_id