Analysis of the Quality and Quantity of Antibiotic Prescriptions for Bacterial Respiratory Tract Superinfection in Patients Hospitalized in COVID-19 Wards

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Total Enrollment

400 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-05-01

Study Completion Date

2021-03-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

In this prospective observational study, a quantitative and qualitative analysis of antibiotic prescriptions for presumed respiratory tract (super)infection in patients hospitalized on COVID-19 wards will be made.

Drivers of antibiotic prescription for presumed respiratory tract infection in patients suspected of being infected with COVID-19 or with definite COVID-19 infections will be identified.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Multiplex PCR for Severe Respiratory Infections During the COVID-19 Pandemic

NCT06349707

Viral Pneumonia

COMPLETED

Pattern and Outcomes of Chest Diseases

NCT06053528

Chest--Diseases

UNKNOWN

Clinical Characteristics And Outcome Of COVID-19 Infection In Patients With Chronic Respiratory Diseases.

NCT05054127

Covid19 Chronic Respiratory Disease

UNKNOWN

Prediction for Critical Outcomes of Patients With COVID-19

NCT05124587

Prediction Model COVID-19 Oral Health +1 more

UNKNOWN

Early Identification and Severity Prediction of Acute Respiratory Infectious Disease

NCT04955756

Acute Respiratory Infection Severe Pneumonia Next Generation Sequencing +1 more

UNKNOWN NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Patients hospitalized on a COVID-19 ward for more than 24 hours will be included. Those with one or more antimicrobial prescription(s) for a presumed respiratory tract (super)infection will be identified and every antibiotic dose will be scored as appropriate, inappropriate, suboptimal or unnecessary by at least two infectious disease (ID) specialists, on an independent manner. If the scoring of the two ID specialists will defer, a third ID specialist will come to a conclusion after discussion with the two other ID specialists.

A quantification of the total amount of antibiotics, prescribed for presumed respiratory tract (super)infection will be made for patients with a COVID-19 diagnosis, but also a quantification for every category of appropriateness will be made.

Possible drivers like the degree of hypoxemia, laboratory parameters, qSOFA score, duration of symptoms, age, comorbidities, symptoms,... associated with the prescription of antimicrobials for a presumed respiratory tract (sur)infection will be identified.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

SARS-CoV Infection Antimicrobial Stewardship Respiratory Tract Infections Antibiotic Resistance

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Men and women hospitalized in one of the COVID wards (no data will be collected during a stay on the ICU department) of UZ Brussel for more than 24 hours and willing to sign the informed consent form (or signed by one of their legal representative(s) if unable).

Exclusion Criteria

* patients younger than 18 years old
* patients not willing to sign the informed consent form
* patients hospitalized for a shorter duration than 24 hours on a COVID-19 ward

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No