Medial Border of Laparoscopic D3 Lymphadenectomy for Right Colon Cancer

NCT ID: NCT04518449

Last Updated: 2024-02-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

WITHDRAWN

Study Classification

OBSERVATIONAL

Study Start Date

2022-12-01

Study Completion Date

2025-10-31

Brief Summary

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This study investigats the gastrointestinal functional outcomes of laparoscopic D3 lymphadenectomy for right colon cancer with the medial border along the left side of superior mesenteric artery (SMA) versus the left side of superior mesenteric vein (SMV). This is a single center, prospective cohort study with a sample size of 264 patients. The primary endpoint is the incidence of diarrhea (evaluated using the Diarrhea Assessment Scale) one month after surgery.

Detailed Description

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Conditions

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Colon Cancer

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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SMA group

the medial border along the left side of superior mesenteric artery (SMA)

medial border along the left side of SMA

Intervention Type PROCEDURE

to place the medial border along the left side of SMA in laparoscopic D3 lymphadenectomy for right colon cancer

SMV group

the medial border along the left side of superior mesenteric vein (SMV)

medial border along the left side of SMV

Intervention Type PROCEDURE

to place the medial border along the left side of SMV in laparoscopic D3 lymphadenectomy for right colon cancer

Interventions

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medial border along the left side of SMA

to place the medial border along the left side of SMA in laparoscopic D3 lymphadenectomy for right colon cancer

Intervention Type PROCEDURE

medial border along the left side of SMV

to place the medial border along the left side of SMV in laparoscopic D3 lymphadenectomy for right colon cancer

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Age between 18 and 75 years
* American Society of Anesthesiologists (ASA) score I to III
* A biopsy proven histological diagnosis of colorectal carcinoma
* tumor located at right half of colon
* Undergoing laparoscopic right hemi-colectomy
* preoperative staging cT2-4aN0M0 or cTanyN+M0
* willing to participate and informed consent signed

Exclusion Criteria

* Pregnant or lactating women
* Synchronous colorectal carcinoma
* History of colorectal cancer or other malignant tumors
* Clinical evidence of metastasis
* Preoperative staging cT1N0 or cT4bNany
* Emergency procedure
Minimum Eligible Age

18 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Shanghai Minimally Invasive Surgery Center

OTHER

Sponsor Role lead

Responsible Party

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Cai Zhenghao

Attending surgeon of gastrointestinal surgery,Ruijin Hospital, Shanghai Jiaotong University School of Medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Other Identifiers

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MISC- Medial border of D3

Identifier Type: -

Identifier Source: org_study_id

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