Measurement of Diaphragmatic Dysfunction After Thoracic Surgery

NCT ID: NCT04507594

Last Updated: 2022-11-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-08-06

Study Completion Date

2022-10-30

Brief Summary

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This study aims to measure diaphragmatic dysfunction with ultrasonography and nerve stimulation of the phrenicus nerve, in patients undergoing thoracic surgery for lung and esophageal cancer, and correlate measures of diaphramatic function to clinical postoperative endpoints.

Detailed Description

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Conditions

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Diaphragm Injury Phrenic Nerve Paralysis Thoracic Cancer Postoperative Complications

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Patients undergoing Thoracic Surgery

Lung lobectomy OR esophagus cancer resection

Intervention Type PROCEDURE

Lunge lobectomy (total) Resection of esophagus cancer

Interventions

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Lung lobectomy OR esophagus cancer resection

Lunge lobectomy (total) Resection of esophagus cancer

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Scheduled thoracic resection Surgery for lung- or esophagus cancer. For lung cancer patients, at least one lung lobe has to scheduled for resection

Exclusion Criteria

* Known Diaphragmatic Dysfunction
* Neuromuscular Disease
* Pleural Effusion \> 1cm
* Pneumothorax
* Known Phrenic Nerve Palsy
Minimum Eligible Age

18 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Aarhus University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Peter Juhl-Olsen

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Department of Anaesthesiology and Intensive Care East Section, Aarhus University Hospital

Aarhus N, , Denmark

Site Status

Countries

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Denmark

References

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Norskov J, Skaarup SH, Bendixen M, Tankisi H, Morkved AL, Juhl-Olsen P. Diaphragmatic dysfunction is associated with postoperative pulmonary complications and phrenic nerve paresis in patients undergoing thoracic surgery. J Anesth. 2024 Jun;38(3):386-397. doi: 10.1007/s00540-024-03325-5. Epub 2024 Mar 28.

Reference Type DERIVED
PMID: 38546897 (View on PubMed)

Other Identifiers

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DiaphragmaticDysfunction

Identifier Type: -

Identifier Source: org_study_id

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