Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
154 participants
INTERVENTIONAL
2012-10-23
2022-09-01
Brief Summary
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The infrapatellar fat pad (Hoffa's fat pad) is a structure which is located intra-articularly. Its function is not well known. During knee replacement surgery, some surgeons would prefer removing the whole of the fat pad as this can improve exposure of the knee joint, as it can affect exposure of the knee joint which will in turn make the procedure slightly more efficient. Other surgeons would rather resect the minimum amount and preserve the bulk of the structure as anecdotally this is thought to decrease the level of post operative pain. This surgical step fat pad resection is a very small part of the whole total knee replacement procedure.
A previous retrospective review of patients whose fat pad had been removed showed that they were nearly twice as likely to experience postoperative pain (P = 0.0005), while another study showed that they are at a slight risk of patellar tendon shortening.
A randomised controlled trial of 68 patients did not show any difference in patella tendon length at six months and no difference in pain relief in both groups 3. However this study did not evaluate the functional outcome in both groups.
To our knowledge, there are no RCT looking at the effect of the excision or preservation of the fat pad in TKR and the functional outcomes post operatively.
Study Hypothesis:
Excision of Hoffa's fat pad during total knee replacement surgery does not affect functional outcome, pain level after surgery or the patella tendon length at either one or two years.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Non removal of fat pad
Non removal of fat pad
non removal of fat pad
non removal of fat pad
Removal of fat pad
Removal of fat pad
removal of fat pad
Removal removal of fat pad
Interventions
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removal of fat pad
Removal removal of fat pad
non removal of fat pad
non removal of fat pad
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
2. Primary Knee Replacement for pathologies other than Osteoarthritis.
3. Previous knee fractures around the knee.
4. Previous confirmed intra-articular infections.
5. Non English speaking/reading patients.
18 Years
ALL
Yes
Sponsors
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Liverpool University Hospitals NHS Foundation Trust
OTHER_GOV
Responsible Party
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Principal Investigators
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A Howard
Role: STUDY_DIRECTOR
Liverpool University Hospitals NHS Foundation Trust
Locations
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Broadgreen Hospital
Liverpool, , United Kingdom
Countries
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Other Identifiers
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4263
Identifier Type: -
Identifier Source: org_study_id
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