Extinction Learning in Adults With Tourette Syndrome

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-09-18

Study Completion Date

2023-10-17

Brief Summary

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Aversive sensory phenomena such as premonitory urges play a central role in the behavioral treatment model of tics. Extinction learning and extinction recall are learning processes implicated within this model, but are still understudied for individuals with Tourette syndrome (TS). This study examines extinction learning and extinction recall in adults with TS using an experimental task. This study will also explore the relationship between extinction processes (i.e., extinction learning and extinction recall) and treatment outcomes with behavior therapy. Findings from this investigation will be used to update the behavioral treatment model, which serves as the basis for evidence-based behavioral interventions.

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Detailed Description

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Conditions

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Tourette Syndrome Habit Reversal Training Tic Disorders Tics Comprehensive Behavioral Intervention for Tics

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Habit Reversal Training

Habit Reversal Training (HRT) is a multi-component evidence-based treatment for tics. It will be delivered over 8 hours of treatment.

Group Type EXPERIMENTAL

Habit Reversal Training

Intervention Type BEHAVIORAL

Habit Reversal Training (HRT) is a multi-component evidence-based treatment for tics.

Interventions

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Habit Reversal Training

Habit Reversal Training (HRT) is a multi-component evidence-based treatment for tics.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* At least 18 years old,
* Have moderate tic severity or greater as evidenced by a YGTSS Total Tic Score greater than 13 (\>9 for youth with motor or vocal tics only)
* Have not received more than 4 previous sessions of HRT
* Be fluent in English
* Medication free or on a stable dose of psychiatric medication for 8 weeks prior to enrollment.