Assessment of a Special Modality of Back Muscles Strengthening for Postural Deformations in Parkinsonian Patient

NCT ID: NCT04492345

Last Updated: 2024-02-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-06-11

Study Completion Date

2026-06-30

Brief Summary

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Parkinson's patients have postural disorders. These disorders are frequent in Martinique. Physiotherapeutic rehabilitation is essential because these disorders are generally non dopa-sensitive.

Detailed Description

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Postural disorders are very common in Martinique, in patients often having an atypical form of the Parkinson's disease. Physiotherapy rehabilitation is essential because these disorders are generally non-dopa-sensitive. Isokinetic muscle strength may reduce postural disorder in Parkinson's disease.

Isokinetic device rehabilitation promotes maximum muscular contraction at constant speed; the resistance of the machine continuously adapting to the force developed by the subject. As the spinal muscle strength gain is superior to conventional post-rehabilitation motor function, the improvement in postural instability should be greater than that achieved with conventional rehabilitation. A better postural support should thus result in a decrease in the risk of falling and an improvement in the quality of walking.

Conditions

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Parkinson Disease Physical Medicine Rehabilitation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Experimental

Patient with conventional rehabilitation session and isokinetic reeducation during 7 weeks

Group Type EXPERIMENTAL

Isokinetic reeducation

Intervention Type OTHER

Conventional rehabilitation session and isokinetic during 7 weeks

Control

Patient with conventional rehabilitation session during 7 weeks

Group Type OTHER

Conventional reeducation

Intervention Type OTHER

Conventional rehabilitation session during 7 weeks

Interventions

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Isokinetic reeducation

Conventional rehabilitation session and isokinetic during 7 weeks

Intervention Type OTHER

Conventional reeducation

Conventional rehabilitation session during 7 weeks

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patient with Parkinson's disease or atypical parkinsonian syndrome
* Age ≥18 years
* Patient with postural disorders with a cervical arrow\> 6cm in the sagittal plane and / or the axis C7S2 different from 0 in the frontal plane
* UPDRS between 10 and 25/108.
* Antiparkinsonian treatment stabilized for 8 weeks
* MMS test\> 25
* Insured person or beneficiary of social security

Exclusion Criteria

* Patient with a neurological condition other than parkinsonian syndrome
* Patient with rheumatic disease
* Patient with a history of trunk surgery
* Patient with a brain stimulator
* Cardiac pathology not stabilized
* Incapacitated adult, or under guardianship, or under curatorship or under judicial protection curatorship
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital Center of Martinique

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Sabine SOPHIA

Role: PRINCIPAL_INVESTIGATOR

CHU Martinique

Locations

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CHU de Martinique

Le Lamentin, , Martinique

Site Status RECRUITING

Countries

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Martinique

Central Contacts

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Sophia SABINE

Role: CONTACT

+596596488056

Corine CARPIN

Role: CONTACT

+596596592696 ext. 3382

Facility Contacts

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Corine CARPIN

Role: primary

0596592696 ext. 3382

References

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Tiffreau V, Preudhomme M, Defebvre L. Troubles de la statique au cours des affections neurologiques évolutives: syndromes parkinsoniens et pathologies musculaires. Revue du rhumatisme monographies 78 (2011) 26-31

Reference Type BACKGROUND

Hubble RP, Naughton GA, Silburn PA, Cole MH. Trunk muscle exercises as a means of improving postural stability in people with Parkinson's disease: a protocol for a randomised controlled trial. BMJ Open. 2014 Dec 31;4(12):e006095. doi: 10.1136/bmjopen-2014-006095.

Reference Type BACKGROUND
PMID: 25552609 (View on PubMed)

Hutin E et al, Communications orales- Maladie de Parkinson. Effet d'une kinésithérapie standardisée sur la stabilité posturale dans la maladie de Parkinson au stade modéré. CO36-002-f. Annals of Physical and Rehabilitation Medicine 56S (2013) e190-e196.

Reference Type BACKGROUND

Crizzle AM, Newhouse IJ. Is physical exercise beneficial for persons with Parkinson's disease? Clin J Sport Med. 2006 Sep;16(5):422-5. doi: 10.1097/01.jsm.0000244612.55550.7d.

Reference Type BACKGROUND
PMID: 17016120 (View on PubMed)

Frazzitta G, Ferrazzoli D, Maestri R, Rovescala R, Guaglio G, Bera R, Volpe D, Pezzoli G. Differences in muscle strength in parkinsonian patients affected on the right and left side. PLoS One. 2015 Mar 25;10(3):e0121251. doi: 10.1371/journal.pone.0121251. eCollection 2015.

Reference Type BACKGROUND
PMID: 25806509 (View on PubMed)

Edouard P, Degache F. Guide d'isocinétisme, L'évaluation isocinétique des concepts aux conditions sportives et pathologiques. Elsevier Masson;09/2016.

Reference Type BACKGROUND

Lannuzel A, Edragas R, Lackmy A, Tressieres B, Pelonde V, Kaptue MEN, Mecharles S, Demas A, Francois B, McGovern E, Vidailhet M, Gaymard B, Roze E. Further evidence for a distinctive atypical degenerative parkinsonism in the Caribbean: A new cluster in the French West Indian Island of Martinique. J Neurol Sci. 2018 May 15;388:214-219. doi: 10.1016/j.jns.2018.02.019. Epub 2018 Feb 6.

Reference Type BACKGROUND
PMID: 29525296 (View on PubMed)

DiFrancisco-Donoghue J, Jung MK, Geisel P, Werner WG. Learning effects of the sensory organization test as a measure of postural control and balance in Parkinson's disease. Parkinsonism Relat Disord. 2015 Aug;21(8):858-61. doi: 10.1016/j.parkreldis.2015.05.007. Epub 2015 May 14.

Reference Type BACKGROUND
PMID: 25997862 (View on PubMed)

Lima LO, Cardoso F, Teixeira-Salmela LF, Rodrigues-de-Paula F. Work and power reduced in L-dopa naive patients in the early-stages of Parkinson's disease. Arq Neuropsiquiatr. 2016 Apr;74(4):287-92. doi: 10.1590/0004-282X20160014.

Reference Type BACKGROUND
PMID: 27097000 (View on PubMed)

Durmus B, Baysal O, Altinayar S, Altay Z, Ersoy Y, Ozcan C. Lower extremity isokinetic muscle strength in patients with Parkinson's disease. J Clin Neurosci. 2010 Jul;17(7):893-6. doi: 10.1016/j.jocn.2009.11.014.

Reference Type BACKGROUND
PMID: 20435478 (View on PubMed)

Cano-de-la-Cuerda R, Vela-Desojo L, Miangolarra-Page JC, Macias-Macias Y. Isokinetic dynamometry as a technologic assessment tool for trunk rigidity in Parkinson's disease patients. NeuroRehabilitation. 2014;35(3):493-501. doi: 10.3233/NRE-141142.

Reference Type BACKGROUND
PMID: 25260231 (View on PubMed)

Gracies JM. [Neurorehabilitation in parkinsonian syndromes]. Rev Neurol (Paris). 2010 Feb;166(2):196-212. doi: 10.1016/j.neurol.2009.10.026. Epub 2010 Feb 6. French.

Reference Type BACKGROUND
PMID: 20138321 (View on PubMed)

Tambosco L et al, Communications orales- Maladie de Parkinson. Particularités de la réponse à l'effort chez les patients atteints d'une maladie de Parkinson. CO36-003-f. Annals of Physical and Rehabilitation Medicine 56S (2013) e190-e196.

Reference Type BACKGROUND

Related Links

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https://www.elitemedicale.fr/genu-plus-easytech

Isocinetique\_easytech\_guide\_clinique.pdf

Other Identifiers

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18_RIPH2-10

Identifier Type: -

Identifier Source: org_study_id

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