Stress Induced by the COVID-19 Pandemic and Nonconfinement: Study of Anxiety Factors and Potential Effects on Immunity.

NCT ID: NCT04491071

Last Updated: 2023-04-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-10-22

Study Completion Date

2021-09-29

Brief Summary

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The aim of this project is to evaluate the impact of pandemic and nonconfinement related to anxiety and eventual immune diseases with several standardized questionnaires : Implant Stability Quotient (ISQ) , Generalized Anxiety Disorder-7 (GAD-7), Patient Health Questionnaire -9 (PHQ-9), Post Traumatic Stress Disorder-8 (PTSD-8), and Experiences in Close Relationship Scale (ECRS).

Detailed Description

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The COVID-19 pandemic and prevention strategise have strongly impacted family lives, social lives, professional lives, and income; resulting in increased reporting of stress and anxiety within patients. This risk of infection 'post-confinement' is an additional source of stress for people returning to their professional and social lives. There are evidence showing a relationship between stress, immunity and the prognosis of several infections and inflammatory diseases.

The COVID-19 pandemic and prevention strategise have strongly impacted family lives and induced a high level of anxiety and other types of stress. This risk of infection 'post-confinement' is an additional source of stress for people returning to their professional and social life.

There are evidences showing a relationship between stress, immunity and the prognosis of several infections and inflammatory diseases.

The aim of this project is to launch an online survey that measures population stress felt during the pandemic and post-confinement time and possible effects on eventual immune mediated disorders (allergies, auto-immunity..) through the report of new events or flares. The stress will first be measured on standardized anxiety GAD-7scale but also on more parameters (ISQ, PHQ-9, PTSD-8, and ECR-S). Socio-economic and environmental parameters will be recorded.

Level of anxiety and other stress parameters as well as occurrence of inflammatory events will be measured according to the calendar and confinement /post confinement timing. Risk factors will be looked for, by multi parametric data analysis.

The survey has been built in a user-friendly, accessible way so the investigators can expect a high number of participants (at least 400), especially as people are highly concerned by the situation and will be motivated to take part.

Conditions

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Stress Disorder

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Volunteers

volunteers over 18 years of age

Generalized Anxiety Disorder-7 (GAD 7)

Intervention Type DIAGNOSTIC_TEST

test that will evaluate persistent and excessive worry about a number of different things. People with Generalized Anxiety Disorder may anticipate disaster and may be overly concerned about money, health, family, work, or other issues. Individuals with Generalized Anxiety Disorder find it difficult to control their worry.

Background questionnaire

Intervention Type DIAGNOSTIC_TEST

questionnaire on the living conditions, socio-professional contexts and environmental conditions of the participants

Impact of COVID-19 questionnaire

Intervention Type DIAGNOSTIC_TEST

status of the patient with regard to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 virus)

Confinement and Communication During the COVID-19 Pandemic

Intervention Type DIAGNOSTIC_TEST

know the experience of containment and isolation during the pandemic

Mental Health questionnaire

Intervention Type DIAGNOSTIC_TEST

welfare effect

Patient Health Questionnaire (PHQ-9)

Intervention Type DIAGNOSTIC_TEST

assess depression during the pandemic

Post Traumatic Stress Disorder questionnaire (PTSD-8)

Intervention Type DIAGNOSTIC_TEST

Assessing the trauma of subjects during the pandemic

Experiences in Close Relationship Scale questionnaire (ECR-S)

Intervention Type DIAGNOSTIC_TEST

Measuring social ties and attachment of subjects

Interventions

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Generalized Anxiety Disorder-7 (GAD 7)

test that will evaluate persistent and excessive worry about a number of different things. People with Generalized Anxiety Disorder may anticipate disaster and may be overly concerned about money, health, family, work, or other issues. Individuals with Generalized Anxiety Disorder find it difficult to control their worry.

Intervention Type DIAGNOSTIC_TEST

Background questionnaire

questionnaire on the living conditions, socio-professional contexts and environmental conditions of the participants

Intervention Type DIAGNOSTIC_TEST

Impact of COVID-19 questionnaire

status of the patient with regard to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2 virus)

Intervention Type DIAGNOSTIC_TEST

Confinement and Communication During the COVID-19 Pandemic

know the experience of containment and isolation during the pandemic

Intervention Type DIAGNOSTIC_TEST

Mental Health questionnaire

welfare effect

Intervention Type DIAGNOSTIC_TEST

Patient Health Questionnaire (PHQ-9)

assess depression during the pandemic

Intervention Type DIAGNOSTIC_TEST

Post Traumatic Stress Disorder questionnaire (PTSD-8)

Assessing the trauma of subjects during the pandemic

Intervention Type DIAGNOSTIC_TEST

Experiences in Close Relationship Scale questionnaire (ECR-S)

Measuring social ties and attachment of subjects

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Adult volunteer who agreed to answer the questionnaires
* Age ≥ 18 years old
* Adult affiliated or having a duty to a social security scheme

Exclusion Criteria

* Children under 18 years old
* Inability to understand information letter, consent, or to use online questionnaire
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Centre Hospitalier Universitaire de Saint Etienne

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Claude LAMBERT, MD PhD HDR

Role: PRINCIPAL_INVESTIGATOR

CHU SAINT-ETIENNE

Locations

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Centre Hospitalier Universitaire de Saint-Etienne

Saint-Etienne, , France

Site Status

Centre de Recherche et d'Innovation Clinique

Glasgow, , United Kingdom

Site Status

Countries

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France United Kingdom

Other Identifiers

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IRBN972020/CHUSTE

Identifier Type: OTHER

Identifier Source: secondary_id

20CH129

Identifier Type: -

Identifier Source: org_study_id

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