Effect of Moringa Oleifera Capsule in Increasing Breast Milk Volume in Early Postpartum Patients

NCT ID: NCT04487613

Last Updated: 2022-07-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

88 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-03-15

Study Completion Date

2022-06-30

Brief Summary

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The purpose of this study is to assess the effect of Moringa oleifera leaf capsule in increasing breast milk volume

Detailed Description

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Conditions

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Postpartum Women

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Moringa oleifera leaf

Participants received Moringa oleifera leaf 450 mg capsule orally twice daily for 3 days.

Group Type ACTIVE_COMPARATOR

Moringa oleifera leaf

Intervention Type DRUG

450 mg capsule

Placebo

Participants received placebo capsule orally twice daily for 3 days.

Group Type PLACEBO_COMPARATOR

Placebo

Intervention Type DRUG

placebo capsule

Interventions

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Moringa oleifera leaf

450 mg capsule

Intervention Type DRUG

Placebo

placebo capsule

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Postpartum women

Exclusion Criteria

* Postpartum women with contraindication for breast feeding such as HIV, untreated tuberculosis, on chemotherapeutic drugs, on radioactive drugs, substance abuse.
* Postpartum women with unstable conditions such as postpartum hemorrhage.
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Chulalongkorn University

OTHER

Sponsor Role lead

Responsible Party

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Vorapong Phupong

Prof. Vorapong Phupong

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Faculty of Medicine, Chulalongkorn University

Bangkok, , Thailand

Site Status

Countries

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Thailand

References

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Awaliyah SN, Rachmawati IN, Rahmah H. Breastfeeding self-efficacy as a dominant factor affecting maternal breastfeeding satisfaction. BMC Nurs. 2019 Aug 16;18(Suppl 1):30. doi: 10.1186/s12912-019-0359-6. eCollection 2019.

Reference Type BACKGROUND
PMID: 31427892 (View on PubMed)

Maharlouei N MD, Pourhaghighi A Medical student, Raeisi Shahraki H PhD, Zohoori D MD, Lankarani KB MD. Factors Affecting Exclusive Breastfeeding, Using Adaptive LASSO Regression. Int J Community Based Nurs Midwifery. 2018 Jul;6(3):260-271.

Reference Type BACKGROUND
PMID: 30035142 (View on PubMed)

Frawley J, Adams J, Steel A, Broom A, Gallois C, Sibbritt D. Women's Use and Self-Prescription of Herbal Medicine during Pregnancy: An Examination of 1,835 Pregnant Women. Womens Health Issues. 2015 Jul-Aug;25(4):396-402. doi: 10.1016/j.whi.2015.03.001. Epub 2015 Apr 29.

Reference Type BACKGROUND
PMID: 25935822 (View on PubMed)

Zapantis A, Steinberg JG, Schilit L. Use of herbals as galactagogues. J Pharm Pract. 2012 Apr;25(2):222-31. doi: 10.1177/0897190011431636.

Reference Type BACKGROUND
PMID: 22392841 (View on PubMed)

Raguindin PF, Dans LF, King JF. Moringa oleifera as a Galactagogue. Breastfeed Med. 2014 Jul-Aug;9(6):323-4. doi: 10.1089/bfm.2014.0002. Epub 2014 Jun 3. No abstract available.

Reference Type BACKGROUND
PMID: 24892837 (View on PubMed)

Stohs SJ, Hartman MJ. Review of the Safety and Efficacy of Moringa oleifera. Phytother Res. 2015 Jun;29(6):796-804. doi: 10.1002/ptr.5325. Epub 2015 Mar 24.

Reference Type BACKGROUND
PMID: 25808883 (View on PubMed)

Butte NF, Wong WW, Patterson BW, Garza C, Klein PD. Human-milk intake measured by administration of deuterium oxide to the mother: a comparison with the test-weighing technique. Am J Clin Nutr. 1988 May;47(5):815-21. doi: 10.1093/ajcn/47.5.815.

Reference Type BACKGROUND
PMID: 2834941 (View on PubMed)

Paritakul P, Ruangrongmorakot K, Laosooksathit W, Suksamarnwong M, Puapornpong P. The Effect of Ginger on Breast Milk Volume in the Early Postpartum Period: A Randomized, Double-Blind Controlled Trial. Breastfeed Med. 2016 Sep;11:361-5. doi: 10.1089/bfm.2016.0073. Epub 2016 Aug 9.

Reference Type RESULT
PMID: 27505611 (View on PubMed)

Fungtammasan S, Phupong V. The effect of Moringa oleifera capsule in increasing breastmilk volume in early postpartum patients: A double-blind, randomized controlled trial. PLoS One. 2021 Apr 6;16(4):e0248950. doi: 10.1371/journal.pone.0248950. eCollection 2021.

Reference Type DERIVED
PMID: 33822798 (View on PubMed)

Other Identifiers

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704/2020

Identifier Type: -

Identifier Source: org_study_id

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