Efficacy of the Extract of Carica Papaya as an Inhibitor of Streptococcus Mutans
NCT ID: NCT04485520
Last Updated: 2021-08-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
40 participants
INTERVENTIONAL
2017-09-21
2017-10-21
Brief Summary
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Detailed Description
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* To determine the inhibition of the extract of the peel of Carica Papaya (baby) at 3% on Streptococcus Mutans by age and sex grouping.
* To quantify the inhibition of the extract of the peel of Carica Papaya (baby) at 3% on the growth of Streptococcus Mutans before, at 10 minutes and 8 days of use in the experimental group.
* Quantify the inhibition of 0.12% Chlorhexidine Gluconate on the growth of Streptococcus Mutans before, after 10 minutes and 8 days of use in the control group.
* Compare the count of Colony Forming Units (CFU) between both groups.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
SINGLE
Study Groups
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Carica Papaya extract
Carica Papaya at 3%
CARICA PAPAYA MOUTHWASH
Each application was 10 ml. applied for 1 minute, once a day for 8 days
Chlorhexidine
0.12% chlorhexidine mouthwash formulation (commercially available)
CHLORHEXIDINE MOUTHWASH
Each application was 10 ml. applied for 1 minute, once a day for 8 days
Interventions
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CARICA PAPAYA MOUTHWASH
Each application was 10 ml. applied for 1 minute, once a day for 8 days
CHLORHEXIDINE MOUTHWASH
Each application was 10 ml. applied for 1 minute, once a day for 8 days
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
* ongoing medical or dental treatment that could interfere with the results.
18 Years
ALL
Yes
Sponsors
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Julieta María Méndez Romero
OTHER
Responsible Party
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Julieta María Méndez Romero
Head of Writting and Publication Department, Regional Health Research Institute
Principal Investigators
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Diego Céspedes
Role: PRINCIPAL_INVESTIGATOR
Facultad de Odontología, Universidad Nacional de Caaguazu
Ulises A Villasanti Torales
Role: STUDY_DIRECTOR
Facultad de Odontologia, Universidad Nacional de Caaguazu
Locations
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Facultad de Odontología Universidad Nacional de Caaguazú
Coronel Oviedo, International, Paraguay
Countries
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References
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Saliasi I, Llodra JC, Bravo M, Tramini P, Dussart C, Viennot S, Carrouel F. Effect of a Toothpaste/Mouthwash Containing Carica papaya Leaf Extract on Interdental Gingival Bleeding: A Randomized Controlled Trial. Int J Environ Res Public Health. 2018 Nov 27;15(12):2660. doi: 10.3390/ijerph15122660.
Other Identifiers
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00140
Identifier Type: -
Identifier Source: org_study_id
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