A Retrospective Study on Laser Treatment of Nevus of Ota in Thai Patients

NCT ID: NCT04481178

Last Updated: 2020-09-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

79 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-09-15

Study Completion Date

2020-12-01

Brief Summary

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A retrospective study on efficacy and complication of laser treatment (Q-switched Nd:YAG and picosecond laser) of nevus of Ota in Thai patients

Detailed Description

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Nevus of Ota is a benign dermal melanocytic nevus found most commonly in Asians. About 50-60% of all cases have the age of onset at birth or within the first year of life, others appear before puberty. It typically presents as a unilateral mottled blue-gray macules and patches distributed along the first and second branches of trigeminal nerve. Due to its marked hyperpigmentation on the face which does not resolved spontaneously, patients may experience psychosocial disturbances and often seek for treatments. Based on selective photothermolysis theory, Q-switched lasers (ruby 694nm, alexandrite 755nm, Nd:YAG 1064nm) have been used for the treatment of nevus of Ota with a success rate of 95% after 6-8 sessions. Reported complications from the lasers are hypopigmentation(15.3%), hyperpigmentation(2.9%), texture changes (2.9%), and scarring (1.9%). Siriraj Skin Laser Center provides laser treatment for nevus of Ota using mainly Q-switched Nd:YAG laser and Picosecond laser. The study of efficacy and complications of Q-switched Nd:YAG and Picosecond laser in the treatment of Nevus of Ota in Thai patients has never been reported. Therefore, we conduct a retrospective study on efficacy and complication of laser treatment (Q-switched Nd:YAG and picosecond laser) of nevus of Ota in Thai patients.

Conditions

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Focus on Laser Treatment of Nevus of Ota in Thai Patients

Study Design

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Observational Model Type

OTHER

Study Time Perspective

RETROSPECTIVE

Study Groups

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patients with nevus of Ota

patients with nevus of Ota who had been treated with laser at Siriraj hospital

Laser (QS, Picosecond laser)

Intervention Type OTHER

QS-Nd Yag Laser, Picosecond laser

Interventions

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Laser (QS, Picosecond laser)

QS-Nd Yag Laser, Picosecond laser

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patient with Nevus of Ota
* Complete data between January 2008 - December 2018

Exclusion Criteria

* Incomplete data
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Mahidol University

OTHER

Sponsor Role lead

Responsible Party

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Woraphong Manuskiatti, M.D.

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Faculty of Medicine Siriraj Hospital

Bangkoknoi, Bangkok, Thailand

Site Status

Countries

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Thailand

Central Contacts

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Prof. Woraphong Manuskiatti, M.D.

Role: CONTACT

+6624197000 ext. 4333

Petchlada Achavanuntakul, M.D.

Role: CONTACT

+66896789944

Facility Contacts

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Woraphong Manuskiatti, M.D.

Role: primary

662-419-4333

Rungsima Wanitphakdeedecha, M.D.

Role: backup

662-419-9922

References

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Achavanuntakul P, Manuskiatti W, Wanitphakdeedecha R, Jantarakolica T. Early Treatment Initiation Improves Outcomes in Nevus of Ota: A 10-Year Retrospective Study. Am J Clin Dermatol. 2022 Jan;23(1):105-114. doi: 10.1007/s40257-021-00637-0. Epub 2021 Oct 24.

Reference Type DERIVED
PMID: 34693508 (View on PubMed)

Other Identifiers

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si347/2020

Identifier Type: -

Identifier Source: org_study_id

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