Coping After Breast Cancer - a Randomized Clinical Trial With Two Digital Interventions

NCT ID: NCT04480203

Last Updated: 2022-03-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

390 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-01-15

Study Completion Date

2035-12-31

Brief Summary

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1. Breast cancer patients and age-matched controls are first invited to answer questions on HRQoL.
2. Among responding breast cancer patients, a subset are invited in a randomized clinical trial with two digital interventions for cancer stress management, cognitive based stress management (CBSM) and mindfulness based intervention (MBI), as well as a control group.
3. The goal is to determine whether digital CBSM or MBI can effectively reduce stress levels as compared to a control group. Second, whether these interventions can improve HRQoL (or avoid onset of HRQoL problems) for patients with breast cancer, compared to a control group.

Detailed Description

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After completing the baseline HRQoL assessment, eligible breast cancer patients will be invited to participate in a randomized clinical trial.

Those who are willing will be randomly allocated to one of the following arms: a) Digital cognitive based stress management, b) Digital mindfulness based intervention or c) Control group.

The intervention is based on a revised version of the Stressproffen app, which was developed by the Oslo University Hospital (Lise Solberg Nes, Elin Børøsund and others).

Outcome measures include measures of perceived stress and HRQoL.

Conditions

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Breast Cancer Patients Health, Subjective

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

An intervention study of breast cancer patients with two digital intervention arms and one control group.
Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Investigators Outcome Assessors
Only the staff that have contact with the participants will know who receives which intervention. The statistician and investigators will be masked.

Study Groups

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Cognitive based stress management (CBSM)

Cognitive based digital intervention.

Group Type ACTIVE_COMPARATOR

Stressproffen cognitive based stress management

Intervention Type OTHER

The participants will download an app (Stressproffen 2A) with cognitive based stress management.

Mindfulness based intervention (MBI)

Mindfulness based digital intervention.

Group Type ACTIVE_COMPARATOR

Stressproffen mindfulness based intervention

Intervention Type OTHER

The participants will download an app (Stressproffen 2B) with mindfulness based intervention.

Control

Control arm. No intervention.

Group Type PLACEBO_COMPARATOR

Control

Intervention Type OTHER

The participants will receive no app. (They will be able to download it after the end of the 3 year study).

Interventions

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Stressproffen cognitive based stress management

The participants will download an app (Stressproffen 2A) with cognitive based stress management.

Intervention Type OTHER

Stressproffen mindfulness based intervention

The participants will download an app (Stressproffen 2B) with mindfulness based intervention.

Intervention Type OTHER

Control

The participants will receive no app. (They will be able to download it after the end of the 3 year study).

Intervention Type OTHER

Other Intervention Names

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CBSM MBI

Eligibility Criteria

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Inclusion Criteria

* first occurrence breast cancer diagnosed from Jan 1, 2020
* non-metastatic cancer stage 0-III

Invasive tumors must be:

* HER2 positive (regardless of ER, PR) or
* ER negative
* (may later include other ER+ if not conflict with recruitment for EMIT/OPTIMA)

Exclusion Criteria

* None
Minimum Eligible Age

20 Years

Maximum Eligible Age

69 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Norwegian Institute of Public Health

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Giske Ursin, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Norwegian Institute of Public Health

Locations

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Cancer Registry of Norway

Oslo, , Norway

Site Status RECRUITING

Countries

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Norway

Central Contacts

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Giske Ursin, MD, PhD

Role: CONTACT

+4722451300

Ine M Larsson

Role: CONTACT

+4722928985

Facility Contacts

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Giske Ursin

Role: primary

+47 22928701

Ine Marie Larsson

Role: backup

+4722928985

References

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Svendsen K, Nes LS, Meland A, Larsson IM, Gjelsvik YM, Borosund E, Rygg CM, Myklebust TA, Reinertsen KV, Kiserud CE, Skjerven H, Antoni MH, Chalder T, Mjaaland I, Carlson LE, Eriksen HR, Ursin G. Coping After Breast Cancer: Protocol for a Randomized Controlled Trial of Stress Management eHealth Interventions. JMIR Res Protoc. 2023 May 24;12:e47195. doi: 10.2196/47195.

Reference Type DERIVED
PMID: 37103493 (View on PubMed)

Other Identifiers

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CABC - Kreftfor project - SEB

Identifier Type: -

Identifier Source: org_study_id

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