Multilevel Intervention Based on Colorectal Cancer (CRC) and Cervical Cancer Self-screening in Rural, Segregated Areas

NCT ID: NCT04471194

Last Updated: 2022-12-13

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

48 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-02-18

Study Completion Date

2022-03-01

Brief Summary

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In this study, the investigators will deliver self-sampling human papillomavirus (HPV) tests and fecal immunochemical test (FIT) kits, as well as adapted cancer screening educational materials, by mail to 110 women who are out-of-date for both cervical and colorectal cancer screenings, recruited through federally qualified health centers (FQHCs) in rural, segregated counties of Pennsylvania.

The hypothesis is that delivering self-sampling HPV tests and FIT, as well as adapted educational materials, to women in rural, segregated areas could help increase cancer screening, reduce geographic cancer disparities, and improve public health.

Detailed Description

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In this study, the investigators will deliver self-sampling human papillomavirus (HPV) tests and fecal immunochemical test (FIT) kits, as well as adapted cancer screening educational materials, by mail to 110 women who are out-of-date for both cervical and colorectal cancer screenings, recruited through federally qualified health centers (FQHCs) in rural, segregated counties of Pennsylvania. A control group of 110 women, also recruited through FQHCs in rural, segregated counties of Pennsylvania, will be used for comparison; these women will receive standard-of-care reminders for cancer screening and complete the baseline and follow-up surveys.

The hypothesis is that delivering self-sampling HPV tests and FIT, as well as adapted educational materials, to women in rural, segregated areas could help increase cancer screening, reduce geographic cancer disparities, and improve public health.

Conditions

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Colorectal Cancer Screening Cervical Cancer Screening

Keywords

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Environmental barriers to cancer screening Person-level barriers to cancer screening

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SCREENING

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

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Self-Sampling Intervention

Participants in this group will receive cervical and colorectal cancer self-sampling kits, instructions for completing the self-sampling kits, and educational materials about cervical and colorectal cancer.

Group Type EXPERIMENTAL

Self-sampling HPV test

Intervention Type DIAGNOSTIC_TEST

Tests for human papillomavirus from cervical cell sample

Fecal occult blood test

Intervention Type DIAGNOSTIC_TEST

Tests for human hemoglobin from blood in fecal samples

Control

Participants in this group will receive a standardized letter informing them that they are out-of-date for both cervical and colorectal cancer screenings and should schedule an appointment with their provider to receive these screenings.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Self-sampling HPV test

Tests for human papillomavirus from cervical cell sample

Intervention Type DIAGNOSTIC_TEST

Fecal occult blood test

Tests for human hemoglobin from blood in fecal samples

Intervention Type DIAGNOSTIC_TEST

Other Intervention Names

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Evalyn® Brush InSure® test

Eligibility Criteria

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Inclusion Criteria

* lives in rural, segregated county of Pennsylvania
* able to speak, read, and communicate well in English
* out of date for both cervical and colorectal cancer screening

Exclusion Criteria

* has had a partial or complete hysterectomy
* has a family history of colorectal cancer
* has a personal history of cervical or colorectal cancer
* persons who are cognitively impaired
* persons who are incarcerated
Minimum Eligible Age

50 Years

Maximum Eligible Age

65 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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National Cancer Institute (NCI)

NIH

Sponsor Role collaborator

Milton S. Hershey Medical Center

OTHER

Sponsor Role lead

Responsible Party

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Jennifer L. Moss, PhD

Assistant Professor, Department of Family and Community Medicine / Department of Public Health Sciences

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jennifer Moss, PhD

Role: PRINCIPAL_INVESTIGATOR

Penn State College of Medicine

Locations

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Penn State College of Medicine

Hershey, Pennsylvania, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Document Type: Informed Consent Form

View Document

Other Identifiers

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K22CA225705-01A1

Identifier Type: NIH

Identifier Source: secondary_id

View Link

STUDY00015480

Identifier Type: -

Identifier Source: org_study_id