Predictive Factor Study of the Occurrence of Endometrial Cancer in Patients With Lynch Syndrome
NCT ID: NCT04452266
Last Updated: 2021-03-09
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
150 participants
OBSERVATIONAL
2020-08-14
2020-10-20
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Endometrial cancer is the third women cancer in France. Many risk factors are known in general population. Lots of factors are related to over exposure to estrogen.
Data about influence of general risk factors in Women with Lynch Syndrome are poor. Recently, a cohort study appears to have shown a significant decrease in the risk of endometrial cancer with multiparity, the use of hormonal contraception and late menopause in Lynch women. The impact of weight and certain metabolic parameters on the occurrence of endometrial cancers remains poorly known to this day.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Intrauterine Levonorgestrel and Observation or Observation Alone in Preventing Atypical Endometrial Hyperplasia and Endometrial Cancer in Women With Hereditary Non-Polyposis Colorectal Cancer or Lynch Syndrome
NCT00566644
Study of the Prevalence of Endometriosis and Adenomyosis
NCT06211569
Endometriosis and Frequency of Endometriosis-associated Ovarian Carcinomas (EAOC)
NCT01732432
Diagnostic and Prognostic Markers of Endometriosis in Menstrual Blood
NCT06245512
Uterine Allotransplantations Using Uterine Grafts From Brain-dead Female Donors
NCT02637674
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
CASE_CONTROL
RETROSPECTIVE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
case group
Women with Lynch Syndrome and endometrial Cancer matched on age of endometrial cancer diagnosis
questionnaire assesment
Each patient will to answer questions about their medical history.
control group
Women with Lynch Syndrome, without Cancer at Lynch Syndrome Diagnostic matched on their age at Lynch Diagnostic
questionnaire assesment
Each patient will to answer questions about their medical history.
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
questionnaire assesment
Each patient will to answer questions about their medical history.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Alive at study time
* Age over 30 at endometrial cancer or Lynch Syndrome Diagnosis
Case group :
\- No cancer before endometrial cancer diagnosis
Control group :
* No endometrial cancer developped
* Free cancer women at Lynch Syndrome diagnosis
Exclusion Criteria
* Poor understanding of the French language
* Other cancer diagnosed before endometrial cancer
* Hysterectomy before lynch diagnosis for free cancer women
30 Years
FEMALE
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
University Hospital, Lille
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Solveig MENU-HESPEL, MD
Role: PRINCIPAL_INVESTIGATOR
University Hospital, Lille
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Hôpital Jeanne de Flandres
Lille, , France
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
2020-A00843-36
Identifier Type: OTHER
Identifier Source: secondary_id
2020_07
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.