Edwards PASCAL Transcatheter Valve Repair System Registry

NCT ID: NCT04443218

Last Updated: 2024-07-26

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

View full results

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Total Enrollment

220 participants

Study Classification

OBSERVATIONAL

Study Start Date

2019-05-27

Study Completion Date

2021-05-10

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This registry will collect prospective and retrospective clinical data on patients treated with the Edwards PASCAL Transcatheter Valve Repair System outside of the Post-Market Clinical Follow-up (PMCF) study.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Patients treated per standard of care at their medical facilities and a written informed consent will be collected to allow the data to be collected. This registry intends to enroll patients under commercial usage and will serve as a mechanism to collect clinical data to further characterize the safety, performance and effectiveness of the PASCAL Transcatheter Valve Repair System.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Mitral Valve Insufficiency

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

COHORT

Study Time Perspective

OTHER

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Edwards PASCAL Transcatheter Valve Repair System

The Edwards PASCAL Valve Repair System is indicated for the percutaneous reconstruction of an insufficient mitral valve.

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patient signs informed consent to participate in the registry
* Patient is intended to or has received the PASCAL device

Exclusion Criteria

* Patient does not consent to participate
* Patient is part of an ongoing Edwards Pre or Post Market Clinical study for the PASCAL Transcatheter Valve Repair System.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Edwards Lifesciences

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Joerg Hausleiter, Prof.

Role: PRINCIPAL_INVESTIGATOR

MD

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

LMU Klinikum der Universität München

München, Bavaria, Germany

Site Status

Immanuel Klinikum Bernau

Bernau bei Berlin, Brandenburg, Germany

Site Status

Universitätsklinikum Gießen

Giessen, Hesse, Germany

Site Status

Georg-August-Universität Göttingen, Universitätsmedizin Göttingen

Göttingen, Lower Saxony, Germany

Site Status

Herzzentrum Köln

Cologne, Nord Rhine Westphalia, Germany

Site Status

Herz- und Diabeteszentrum NRW - Bad Oeynhausen

Bad Oeynhausen, North Rhine-Westphalia, Germany

Site Status

Herzzentrum der Universitätsklinik Bonn

Bonn, North Rhine-Westphalia, Germany

Site Status

St.-Johannes-Hospital Dortmund

Dortmund, North Rhine-Westphalia, Germany

Site Status

Elisabeth-Krankenhaus Essen

Essen, North Rhine-Westphalia, Germany

Site Status

Universitätsmedizin der Johannes Gutenberg Universität Mainz

Mainz, Rhineland-Palatinate, Germany

Site Status

Herzzentrum Universitätsklinik Dresden

Dresden, Saxony, Germany

Site Status

Heart Centre of the University Leipzig

Leipzig, Saxony, Germany

Site Status

Kath. Marienkrankenhaus Hamburg GmbH

Hamburg, , Germany

Site Status

Inselspital Bern

Bern, , Switzerland

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Germany Switzerland

Provided Documents

Download supplemental materials such as informed consent forms, study protocols, or participant manuals.

Document Type: Study Protocol

View Document

Document Type: Statistical Analysis Plan

View Document

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

2019-03

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

MitraClip® Registry
NCT02033811 RECRUITING