Analgesia After Knee Arthroscopy :Dexmedetomidine vs Fentanyl

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

45 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-07-01

Study Completion Date

2020-12-01

Brief Summary

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The aim of this study is to evaluate analgesic effects Bupivacaine, Bupivacaine plus Dexmedetomidine and Bupivacaine plus Fentanyl in relieving pain after knee arthroscopic surgery.

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Detailed Description

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Forty-five patients ASA I - II aged 21-45 years for elective knee arthroscopy were divided into 3 groups: Group B, BD and BF. Group B received Intra-articular injection of 20 ml bupivacaine 0.25%+ 1 ml saline. Group BD received Intra-articular injection of 20 ml bupivacaine 0.25%+ 1 ml dexmedetomidine (100 ug).

Group BF received Intra-articular injection of 20 ml bupivacaine 0.25%+ 1 fentanyl (50 ug). The time of first request of analgesia and analgesic effect by VAS during the first 24 hr. postoperatively are recorded.

Conditions

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Analgesia

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

analgesia for postoperative pain after knee arthroscopy: dexmedetomidine+bupivacaine, fentanyl+bupivacaine , bupivacaine

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors

anesthetist not sharing in the study will assess patient

Study Groups

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group B

IGroup B received Intra-articular injection of 20 ml bupivacaine 0.25%+ 1 ml saline

Group Type ACTIVE_COMPARATOR

Bupivacain

Intervention Type DRUG

Group B received Intra-articular injection of 20 ml bupivacaine 0.25%+ 1 ml saline.

group BD

. Group BD received Intra-articular injection of 20 ml bupivacaine 0.25%+ 1 ml dexmedetomidine (100 ug).

Group Type ACTIVE_COMPARATOR

Dexmedetomidine

Intervention Type DRUG

Group BD received Intra-articular injection of 20 ml bupivacaine 0.25%+ 1 ml dexmedetomidine (100 ug).

Bupivacain

Intervention Type DRUG

Group B received Intra-articular injection of 20 ml bupivacaine 0.25%+ 1 ml saline.

group BF

Group BF received Intra-articular injection of 20 ml bupivacaine 0.25%+ 1 fentanyl (50 ug).

Group Type ACTIVE_COMPARATOR

Fentanyl

Intervention Type DRUG

Group BF received Intra-articular injection of 20 ml bupivacaine 0.25%+ 1 fentanyl (50 ug)

Bupivacain

Intervention Type DRUG

Group B received Intra-articular injection of 20 ml bupivacaine 0.25%+ 1 ml saline.

Interventions

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Dexmedetomidine

Group BD received Intra-articular injection of 20 ml bupivacaine 0.25%+ 1 ml dexmedetomidine (100 ug).

Intervention Type DRUG

Fentanyl

Group BF received Intra-articular injection of 20 ml bupivacaine 0.25%+ 1 fentanyl (50 ug)

Intervention Type DRUG

Bupivacain

Group B received Intra-articular injection of 20 ml bupivacaine 0.25%+ 1 ml saline.

Intervention Type DRUG

Other Intervention Names

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precedex marcaine

Eligibility Criteria

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Inclusion Criteria

* Either sex,
* Age 21-45 years,
* American Society of Anesthesia (ASA) I - II for elective knee arthroscopy.

Exclusion Criteria

* The patients with history of hepatic and renal diseases, psychiatric disorders,
* Prolonged intake of (NSAIDS, opioids and tricyclic antidepressant),
* Allergy to study drugs and patient who received analgesics up to 24 hr. before surgery were excluded from this study.

Minimum Eligible Age

21 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes