Brain Hippocampal Volume Relationship With Anxious Symptoms in Major Depressive Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-07-01

Study Completion Date

2020-12-31

Brief Summary

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The objective of this transversal study is to determine if there is a difference in the volume of the hippocampus with the degree of anxiety.

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Detailed Description

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Conditions

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Major Depressive Disorder Anxiety Disorders

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

NONE

Study Groups

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Volumetric changes in response to sertraline or escitalopram

Group Type OTHER

Sertraline

Intervention Type DRUG

Sertraline will be started in all patients, unless it is contraindicated, in this case, Escitalopram will be indicated.

Interventions

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Sertraline

Sertraline will be started in all patients, unless it is contraindicated, in this case, Escitalopram will be indicated.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* First-time patients, without prior antidepressant treatment that meet the diagnostic criteria of DSM 5 for major depressive disorder.
* Patients who meet the current major depressive disorder criteria in the MINI interview.
* Patients who signed the informed consent for the investigation.

Exclusion Criteria

* Patients presenting insufficient data in the MINI interview for current major depression.
* Patients diagnosed with intellectual development disorder, by clinic.
* Patients with diagnosis of the schizophrenic spectrum, bipolar disorder, autism spectrum disorder, post-traumatic stress disorder and obsessive-compulsive disorder by clinic and / or by the MINI interview.
* Patients with contraindications for MRI.
* Patients with serious or unstable medical problems.
* Patients undergoing some legal procedure.
* Patients with difficulties in understanding the interview or completing the assessment instruments.

Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No