Early Systolic Notching in Pulmonary Embolism

NCT ID: NCT04413825

Last Updated: 2021-02-03

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 180 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2020-06-15
• Study Completion Date: 2021-01-15

Brief Summary

Venous thromboembolism (VTE), clinically seen as deep vein thrombosis (DVT) or pulmonary embolism (PE), is the third most common acute cardiovascular syndrome after myocardial infarction and stroke. In a study conducted by critical care and emergency physicians, lung ultrasonography (US) for pleural infarction areas, lower extremity venous US in terms of DVT, and focused cardiac US in terms of right ventricular strain were demonstrated with different diagnostic values for PE. However, no ultrasonographic method alone has a high diagnostic value for PE alone in the literature. In a recent study, it is stated that a new cardiac finding (early systolic notch- ESN) has high sensitivity (92%) and specificity (99%) in massive and submassive emboli. However, the limited patient population and the exclusion of many patient groups limits the applicability of the study and its use in other patient groups. With this study, it was aimed to determine the diagnostic value of ESN finding within the emergency department conditions by keeping the patient population wider.

Conditions

Pulmonary Embolism

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Eligibility Criteria

Inclusion Criteria

• Patients undergoing pulmonary CT angiography with suspicion of pulmonary embolism

Exclusion Criteria

• Pregnant women,
• Patients under 18 years of age,
• Those who received thrombolytic therapy,
• Poor ultrasound imaging.

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Akdeniz University

OTHER

Sponsor Role: collaborator

Ege University

OTHER

Sponsor Role: collaborator

Antalya Training and Research Hospital

OTHER_GOV

Sponsor Role: collaborator

Rize Üniversitesi

OTHER

Sponsor Role: collaborator

Izmir Katip Celebi University

OTHER

Sponsor Role: collaborator

Gazi University

OTHER

Sponsor Role: lead

Responsible Party

Mehmet Ali Aslaner

Assos. Prof.

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Gazi University Facaulty of Medicine

Ankara, , Turkey (Türkiye)

Countries

Turkey (Türkiye)

Other Identifiers

Gazi U.

Identifier Type: -

Identifier Source: org_study_id