Comparison of Sleep Disordered Breathing Events Detected by the CPAP Device "prismaLine" With Polysomnography

NCT ID: NCT04407949

Last Updated: 2020-10-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

70 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-01-17

Study Completion Date

2020-09-30

Brief Summary

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Evaluation of residual sleep disordered breathing (SDB) under continuous positive airway pressure (CPAP) therapy with comparison of the automatic detected SDB event indices from CPAP machines with manual scored polysomnography (PSG).

Detailed Description

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The evaluation of residual sleep disordered breathing (SDB) in sleep apnea (SA) after initiation of continuous positive airway pressure (CPAP) therapy is important to verify the therapeutic success. In clinical practice, the internal records of CPAP devices are utilized to determine the therapeutic success, during either medical consultations or telemetric observation.

This study was designed to evaluate the quality of SDB Event Indices (EI), which are recorded by the CPAP device (Prisma, Löwenstein Medical Technology).

The detected events of a manual scored polysomnography (PSG) in the sleep laboratory will be compared with the simultaneously recorded events of the CPAP device.

This shall lead to recommendations regarding the situations, and in which degree the event detection of the CPAP devices may be meaningful to determine the therapeutic success of home sleep apnea therapy.

Conditions

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Sleep Apnea Syndromes

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Every enrolled patient underwent a CPAP - Titration under PSG with predefined pressure steps. Afterwards breathing events are scored manually based on AASM Criteria by a trained study member. The events will be compared with the readout from the CPAP Device.
Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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event detection

Group Type OTHER

CPAP Treatment

Intervention Type OTHER

Comparing events from the CPAP device with the events scored in PSG

Interventions

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CPAP Treatment

Comparing events from the CPAP device with the events scored in PSG

Intervention Type OTHER

Other Intervention Names

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PrismaLine

Eligibility Criteria

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Inclusion Criteria

* PSG diagnostic not older than 3 month,
* AHI\>15, CPAP indication,
* age \>18,
* nasal CPAP mask,
* written informed consent

Exclusion Criteria

* CPAP contraindication,
* participation in another clinical trial
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Heinen und Löwenstein GmbH & Co. KG

INDUSTRY

Sponsor Role collaborator

Institut für Pneumologie Hagen Ambrock eV

INDUSTRY

Sponsor Role lead

Responsible Party

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Georg Nilius, PD DR med

medical director of pneumologic department

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Georg Nilius, MD

Role: PRINCIPAL_INVESTIGATOR

Kliniken Essen-Mitte, Evang. Huyssens-Stiftung/Knappschaft gGmbH

Locations

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Kliniken Essen-Mitte, Evang. Huyssens-Stiftung/Knappschaft gGmbH

Essen, North Rhine-Westphalia, Germany

Site Status

Countries

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Germany

References

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Richter M, Schroeder M, Domanski U, Schwaibold M, Nilius G. Reliability of respiratory event detection with continuous positive airway pressure in moderate to severe obstructive sleep apnea - comparison of polysomnography with a device-based analysis. Sleep Breath. 2023 Aug;27(4):1639-1650. doi: 10.1007/s11325-022-02740-w. Epub 2022 Nov 17.

Reference Type DERIVED
PMID: 36394692 (View on PubMed)

Other Identifiers

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EventLab

Identifier Type: -

Identifier Source: org_study_id

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