Different Timing for Early Laparoscopic Cholecystectomy in Acute Calcular Cholecystitis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

900 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-04-01

Study Completion Date

2020-03-25

Brief Summary

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The ideal timing for ELC continues to be debatable in patients with acute calculator cholecystitis (ACC). This study was planned to identify the impact of different ELC timing in ACC on surgical outcomes in terms of safety and efficacy

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Detailed Description

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This multicentric analysis involved of successive patients with ACC ELC between April 2018 and March 2020. Patients were divided into three groups according to the timing of the surgery: from the onset of symptoms within the first 3 days (group 1), between 4 and 7 days (group 2), and beyond 7 days (group 3). The primary outcome was the incidence of postoperative complications The secondary outcomes were conversion rate, blood loss, operative times, operational difficulty, the cost-benefit relationship, postoperative stay with each treatment line.

Conditions

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Acute Cholecystitis

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Patients with ACC were divided into three groups according to the timing of the surgery: from the onset of symptoms within the first 3 days (group 1), between 4 and 7 days (group 2) and beyond 7 days (group 3).

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Patients were divided into three groups according to the timing of the surgery: from the onset of symptoms within the first 3 days (group 1), between 4 and 7 days (group 2) and beyond 7 days (group 3).

Study Groups

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from the onset of symptoms within the first 3 days (group 1)

ELC for ACC from the onset of symptoms within the first 3 days (group 1)

Group Type ACTIVE_COMPARATOR

from the onset of symptoms within the first 3 days

Intervention Type PROCEDURE

ELC within 3 days of onset of ACC

from the onset of symptoms within the 4-7 days

ELC for ACC from the onset of symptoms within the4-7 days (group II)

Group Type ACTIVE_COMPARATOR

: from the onset of symptoms within the 4-7 days

Intervention Type PROCEDURE

ELC 4-7days of onset of ACC

from the onset of symptoms beyond 7 days

ELC for ACC from the onset of symptoms beyond 7 days (group III)

Group Type ACTIVE_COMPARATOR

from the onset of symptoms beyond 7 days

Intervention Type PROCEDURE

ELC after 7days of onset of ACC

Interventions

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from the onset of symptoms within the first 3 days

ELC within 3 days of onset of ACC

Intervention Type PROCEDURE

: from the onset of symptoms within the 4-7 days

ELC 4-7days of onset of ACC

Intervention Type PROCEDURE

from the onset of symptoms beyond 7 days

ELC after 7days of onset of ACC

Intervention Type PROCEDURE

Other Intervention Names

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group 1 Group II Group III

Eligibility Criteria

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Inclusion Criteria

ACC patients who underwent early LC

Exclusion Criteria

Pregnancy, Acalculous cholecystitis, CBDS, Ascending cholangitis, Pancreatitis, ASA score 4, Patients scheduled for DLC with failed medical treatment.

Eligible Sex

ALL

Accepts Healthy Volunteers

No