Effects of Regular Submaximal Exercise on Asthma Control and Quality of Life in Patients With Persistent Symptoms

NCT ID: NCT04395937

Last Updated: 2022-05-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-09-01

Study Completion Date

2023-09-01

Brief Summary

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The effects of regular exercise on asthma control has not yet been well demonstrated.

The aim of this study is to investigate the impact of submaximal physical exercise on quality of life, on symptomatic control, and on bronchial and systemic inflammatory markers in patients with persistant asthma.

Detailed Description

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While it is well known that intense physical exercise can generate bronchospasm and limit exercise performance, it recently appeared that regular physical exercise practiced aerobically could improve the clinical status of asthmatic patients.

The investigators are planning a 12-week randomized controlled study to assess the effect of regular aerobic exercise on quality of life, asthma control, bronchial hyperresponsiveness and bronchial and systemic inflammation in patients with persistent asthma

The hypothesis is that regular physical exercise increases control and quality of life and reduces inflammation and bronchial hyperresponsiveness compared to simple physiotherapy sessions.

Conditions

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Chronic Asthma

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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respiratory physiotherapy

exercises to improve the way of breathing

Group Type ACTIVE_COMPARATOR

exercises

Intervention Type OTHER

One hour twice a week to practice respiratory exercises, postural exercises, muscular exercises

respiratory physiotherapy and physical exercises

intensity determined by the VO2max measured during ergospirometric measure

Group Type EXPERIMENTAL

exercises

Intervention Type OTHER

One hour twice a week to practice respiratory exercises, postural exercises, muscular exercises

control group

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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exercises

One hour twice a week to practice respiratory exercises, postural exercises, muscular exercises

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* asthmatic patient
* aged 18- 90 years
* ACQ \> 1.5
* stable background treatment comprising at least one inhaled corticosteroid or an anti-leukotriene

Exclusion Criteria

* IMC \> 35
* severe osteoarthritis of the knees and hips
* unstable angor
* Severe uncontrolled hypertension
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Liege

OTHER

Sponsor Role lead

Responsible Party

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Renaud Louis

Professor Doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Chu Liege

Liège, Liege, Belgium

Site Status RECRUITING

Countries

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Belgium

Central Contacts

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Stephanie Ziant

Role: CONTACT

+3243668568

Facility Contacts

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stephanie ziant

Role: primary

+3243668568

Other Identifiers

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B707202042981

Identifier Type: -

Identifier Source: org_study_id

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