Evaluation of Clinical Parameters on Admission and Medications in Covid-19 Pneumonia (Corona Virus Disease 2019)

NCT ID: NCT04379310

Last Updated: 2020-06-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

54 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-05-01

Study Completion Date

2020-05-08

Brief Summary

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Investigators will recruit patients diagnosed with COVID-19 pneumonia between March 11th, 2020 and April 15th, 2020 in emergency, internal medicine and cardiology outpatient clinics, retrospectively and analyze their clinical and demographic features on admission in regard to their medications used for chronic diseases regularly.

Detailed Description

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Covid-19 infections demonstrated a pandemic spread after January 2020 and their associations with patient characteristics and comorbidities are intensely studied. Investigators also want to find out potential relations between major medications taken for chronic diseases and clinical parameters of patients with Covid-19 pneumonia.

For the study, investigators will recruit patients diagnosed with COVID-19 pneumonia between March 11th, 2020 (the date at which the first case of Covid-19 in Turkey officially declared) and April 15th, 2020 in emergency, internal medicine and cardiology outpatient clinics, retrospectively. All of the demographic features, complaints on admission, reports of computed tomography (CT) scans of the chest without intravenous contrast issued by the staff radiologist, c-reactive protein (CRP) and complete blood count (CBC) values on admission will be recorded retrospectively. Their polymerase chain reaction (PCR) test results will be derived from the hospital records based on public health covid-19 database notifications and list of medications taken regularly for more than 8 weeks before the diagnosis of COVID-19 pneumonia from the national pharmacy database. Information about other systemic diseases and major medical conditions of patients will be procured from the medical histories gained by relevant physicians. Patient taking each drug group will be compared to those not taking that drugs in terms of clinical and demographical features mentioned above. Statistical analysis will be performed by using SPSS software.

Conditions

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Covid-19

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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covid-19 pneumonia

diagnosed with covid-19 by using PCR and computed tomography scans

ACE Inhibitors and Calcium Channel Blockers

Intervention Type DRUG

effect of drugs on patients with covid-19 pneumonia

Interventions

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ACE Inhibitors and Calcium Channel Blockers

effect of drugs on patients with covid-19 pneumonia

Intervention Type DRUG

Other Intervention Names

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NSAID

Eligibility Criteria

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Inclusion Criteria

* Covid-19 pneumonia at least with typical infiltration on CT +/- positive PCR.

Exclusion Criteria

* no typical infiltration and negative PCR results.
* not newly diagnosed.
Minimum Eligible Age

18 Years

Maximum Eligible Age

99 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Istanbul Nisantasi University

OTHER

Sponsor Role lead

Responsible Party

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Murat Civan

M.D.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Hasan Haciosman

Role: STUDY_CHAIR

academic staff, MD

Locations

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Vital Hospital

Bahçelievler, Istanbul, Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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20200504441

Identifier Type: -

Identifier Source: org_study_id

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