COVID-19 in Liver Transplant Recipients

NCT ID: NCT04361591

Last Updated: 2022-08-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

121 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-03-01

Study Completion Date

2021-03-01

Brief Summary

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Prospective observational study aimed at analyzing the incidence, clinical characteristics and outcomes of COVID-19 in LT in Spain.

Detailed Description

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Coronavirus Disease 2019 (COVID-19) is a novel viral disease caused by the SARS-Cov-2 infection with a particular predominance of upper and lower respiratory tract symptoms. First diagnosed in China in late 2019, the virus has progressed to a state of pandemia, involving Spain with a important outbreak.

While the outcomes of viral infections in solid organ transplant (SOT) recipients tend to be worse than those from the general population due to chronic immunosuppression, there is little information on the incidence and outcomes of COVID-19 in liver transplant (LT) recipients. LT recipients are usually under less immunosuppression than other SOT and the clinical expression and outcomes of COVID-19 may be different to the reported outcomes in other SOT.

The Spanish Society of Liver Transplantation, which includes 25 LT programs, has promoted a nationwide registry for LT with COVID-19 to help ascertain the incidence and outcomes and help evidence-based management .

Conditions

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Liver Transplant; Complications COVID19 Respiratory Failure

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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COVID-19

Liver Transplant recipients

Observational only

Intervention Type OTHER

Observational Study

Interventions

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Observational only

Observational Study

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Liver Transplant recipient
* Confirmed (PCR positive) SARS-Cov-2 infection
* Informed Consent
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sociedad Española de Trasplante Hepático

NETWORK

Sponsor Role collaborator

Hospital Clinic of Barcelona

OTHER

Sponsor Role lead

Responsible Party

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Jordi Colmenero

Liver Transplant Hepatologist, SETH Scientific Committee Chair

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Jordi Colmenero

Role: PRINCIPAL_INVESTIGATOR

Sociedad Española de Trasplante Hepático

Locations

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SETH-affiliated Liver Transplant Programs in Spain

Barcelona, , Spain

Site Status

Countries

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Spain

Related Links

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Other Identifiers

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HCB/2020/0384

Identifier Type: -

Identifier Source: org_study_id

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