Photoscreening for Retinoblastoma

NCT ID: NCT04344652

Last Updated: 2025-09-26

Basic Information

• Recruitment Status: WITHDRAWN
• Clinical Phase: NA
• Study Classification: INTERVENTIONAL
• Study Start Date: 2022-06-01
• Study Completion Date: 2022-06-01

Brief Summary

Retinoblastoma is the most common pediatric eye malignancy and manifests between 1 and 5 years of age. The tumor is most often diagnosed by leukocoria ( white reflex in the pupil). There is often a significant delay in diagnosis and early diagnosis enables good life prognosis and better vision outcome.There is currently not a standardized screening protocol for detection of retinoblastoma. Vision screening methods are recommended for children 3-5 years of age. The investigators are attempting to use instrument based screening started from birth to detect leukocoria.

Conditions

Retinoblastoma

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: DIAGNOSTIC
• Blinding Strategy: NONE

Study Groups

Photoscreening

Photoscreening of patients 0 to 10 years of age

Group Type: EXPERIMENTAL

Photoscreening -

Intervention Type: DEVICE

external picture taken with a an phone based app

Interventions

Photoscreening -

external picture taken with a an phone based app

Intervention Type: DEVICE

Eligibility Criteria

Inclusion Criteria

• Age birth to 10 years
• Informed consent given by parent or legal guardian

Exclusion Criteria

• None

• Minimum Eligible Age: 0 Years
• Maximum Eligible Age: 10 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Phoenix Children's Hospital

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Other Identifiers

AR01

Identifier Type: -

Identifier Source: org_study_id