Longitudinal Population-based Observational Study of COVID-19 in the UK Population
NCT ID: NCT04330599
Last Updated: 2025-06-08
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
13000 participants
OBSERVATIONAL
2020-04-27
2026-04-27
Brief Summary
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1. To determine risk factors for incident COVID-19 and for adverse outcomes of COVID-19 in the UK population
2. To characterise the natural history of COVID-19 in the UK population
3. To evaluate the impact of COVID-19 on the physical and mental health of the UK population
4. To provide a resource from which to identify potential participants for future clinical trials, and to use data collected in COVIDENCE as comparison or control data for trial participants who have been randomised to receive one or more interventions.
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Eligibility Criteria
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Inclusion Criteria
* Age ≥16 years
16 Years
ALL
Yes
Sponsors
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King's College London
OTHER
London School of Hygiene and Tropical Medicine
OTHER
University of Edinburgh
OTHER
Swansea University
OTHER
Queen's University, Belfast
OTHER
Barts & The London NHS Trust
OTHER
Queen Mary University of London
OTHER
Responsible Party
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Locations
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Queen Mary University of London
London, County (optional), United Kingdom
Countries
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Central Contacts
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Facility Contacts
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References
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Vivaldi G, Talaei M, Blaikley J, Jackson C, Pfeffer PE, Shaheen SO, Martineau AR. Bidirectional relationship between sleep problems and long COVID: a longitudinal analysis of data from the COVIDENCE UK study. BMJ Open Respir Res. 2025 Jun 15;12(1):e002506. doi: 10.1136/bmjresp-2024-002506.
Vivaldi G, Pfeffer PE, Talaei M, Basera TJ, Shaheen SO, Martineau AR. Long-term symptom profiles after COVID-19 vs other acute respiratory infections: an analysis of data from the COVIDENCE UK study. EClinicalMedicine. 2023 Oct 6;65:102251. doi: 10.1016/j.eclinm.2023.102251. eCollection 2023 Nov.
Tydeman F, Pfeffer PE, Vivaldi G, Holt H, Talaei M, Jolliffe D, Davies G, Lyons RA, Griffiths C, Kee F, Sheikh A, Shaheen SO, Martineau AR. Rebound in asthma exacerbations following relaxation of COVID-19 restrictions: a longitudinal population-based study (COVIDENCE UK). Thorax. 2023 Aug;78(8):752-759. doi: 10.1136/thorax-2022-219591. Epub 2022 Nov 23.
Williamson AE, Tydeman F, Miners A, Pyper K, Martineau AR. Short-term and long-term impacts of COVID-19 on economic vulnerability: a population-based longitudinal study (COVIDENCE UK). BMJ Open. 2022 Aug 23;12(8):e065083. doi: 10.1136/bmjopen-2022-065083.
Holt H, Talaei M, Greenig M, Zenner D, Symons J, Relton C, Young KS, Davies MR, Thompson KN, Ashman J, Rajpoot SS, Kayyale AA, El Rifai S, Lloyd PJ, Jolliffe D, Timmis O, Finer S, Iliodromiti S, Miners A, Hopkinson NS, Alam B, Lloyd-Jones G, Dietrich T, Chapple I, Pfeffer PE, McCoy D, Davies G, Lyons RA, Griffiths C, Kee F, Sheikh A, Breen G, Shaheen SO, Martineau AR. Risk factors for developing COVID-19: a population-based longitudinal study (COVIDENCE UK). Thorax. 2022 Sep;77(9):900-912. doi: 10.1136/thoraxjnl-2021-217487. Epub 2021 Nov 30.
Other Identifiers
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COVIDENCE UK
Identifier Type: -
Identifier Source: org_study_id
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