Bacteriological Study of Acute Follicular Tonsillitis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

66 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-04-30

Study Completion Date

2021-10-31

Brief Summary

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The objective of the study is to answer the following questions :-

1. Is there an actual failure rate in tonsillitis treatment with amoxicillin clavulanate ? If yes,
2. What is (are) the possible reason(s) to explain it in our locality ?

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Detailed Description

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Tonsillitis is one of the most common diseases in the throat that occurs in the younger age group .

The predominant bacteria causing tonsillitis are group A b-haemolytic streptococci (GABHS), which are highly susceptible to the penicillin group of antibiotics.

It has been reported in the literature that the rate of penicillin failure has consistently increased from about 7% in the 1950s to almost 40% in the 2000s.

Authors propose many reasons to explain such failure rates e.g. the coexistence of oropharyngeal beta-lactamase producing bacteria .

Although there were no documented reports, it was observed that there are rising reports of failure in treatment of acute follicular tonsillitis by amoxicillin clavulanate.

Conditions

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Acute Follicular Tonsillitis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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Amoxicillin Clavulanate

Intravenous drug intake of our drug.

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

patients with acute follicular tonsillitis neither younger than five years nor older than 60 years old.

Exclusion Criteria

1. Other causes of tonsillitis that do not cause suppuration .
2. Age below five , and above 60 years .
3. Patients who received antibiotic one week before presentation .
4. Immune compromised patients .
5. Patients with quinsy.

Minimum Eligible Age

5 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No