Storytelling Intervention to Promote Cervical Cancer Screening Uptakes Among Malawian Women Living With Human Immunodeficiency Virus

NCT ID: NCT04307433

Last Updated: 2022-09-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

179 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-10-21

Study Completion Date

2022-08-31

Brief Summary

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To develop a theory-based culturally-grounded storytelling-based intervention to increase cervical cancer screening among Malawian women living with HIV infection. Secondary objectives: To conduct a pilot randomized clinical trial (RCT) to examine the acceptability, feasibility and preliminary effectiveness of narrative intervention on cervical cancer screening prevention behavior.

Detailed Description

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Design

This two year project will employ a holistic community-based approach for recruitment. The project will involve two phases: Phase 1: The investigators will produce culturally-grounded and human-centered storytelling narrative intervention videos to address sociocultural and individual factors which influence cervical cancer prevention behaviors. Phase 2: The investigator will conduct a pilot RCT using the storytelling-based intervention delivered by mHealth (tablets) with 180 women residing in a rural community in Malawi. The intervention groups (Arm 1: storytelling narrative video on tablets \[n=60\] \& Arm 2: a video with a voice over presenting didactic materials on tablets \[n=60\]) will watch approximately 30 minutes of video intervention and the comparison group (Arm 3 \[n=60\]) will be read non-narrative educational materials. Study measures of attitudes, knowledge, and cervical cancer screening intention will be assessed by pre-test and immediate post-test interviews, then again at 2 and 6-months following the intervention.

Selection and Enrollment

Inclusion criteria are: 1) being confirmed HIV positive based on medical records, 2) women living with HIV infection (WLHIV) support group members, 3) ages 20-50 years, 4) no prior cervical cancer screening, 5) no history of invasive cervical cancer, and 6) willingness to participate in the study. The age range to 20-50 years for cervical cancer screening because there is limited evidence that this is the optimal upper age for cervical cancer screening of HIV-infected women (World Health Organization \[WHO\] 2013).

This study will use a sequential-stratified sampling method. Of the eligible support groups and among those expressing interest, the investigators will select 15 support groups from rural areas within the Lilongwe district and then randomly assign the selected groups into intervention and comparison arms. The computer-generated assignments will be stratified by support group size and the distance between intervention and control arms (at least 4 miles). Within each selected support group, 12 women who are eligible will be invited to participate in the study. The investigators have satisfactorily used these methods for recruitment of WLHIV by working with HIV support group leaders in our previous studies.

Conditions

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HIV/AIDS

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

The proposed study has two phases:

Phase 1. Development of Narrative Video: The investigators will first develop culturally-grounded and human-centered storytelling narrative intervention videos in Chichewa, the local language to address sociocultural and individual factors which influence cervical cancer prevention behaviors. The video will be filmed in person in community organizations in Malawi.

Phase 2: A Pilot Randomized Controlled Trial (RCT) of a Story Telling Narrative Intervention: The investigators will conduct a three-arm pilot RCT using the storytelling-based intervention delivered by mHealth (tablets) with 180 women residing in a rural community in Malawi. The intervention groups (Arm 1: storytelling narrative video on tablets \[n=60\] \& Arm 2: a video with a voice over presenting didactic materials on tablets \[n=60\]) will watch approximately 30 minutes of video intervention and the comparison group (Arm 3 \[n=60\]) will be read non-narrative educational materials
Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Outcome Assessors
The data collector who assesses the follow-up assessments will be blind to treatment condition

Study Groups

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Arm 1

ST Narrative + mHealth: Storytelling narrative video on tablets

Group Type EXPERIMENTAL

Storytelling narrative videos on tablets

Intervention Type BEHAVIORAL

The storytelling narrative episodes in the application will feature video clips of the multiple stories of women living with HIV infection, HIV support group leaders, community leaders, and health care professionals and a Learn More video of physician discussing cervical cancer.

Arm 2

mHealth: a video with a voice over presenting didactic materials on tablets

Group Type ACTIVE_COMPARATOR

Storytelling narrative videos on tablets

Intervention Type BEHAVIORAL

The storytelling narrative episodes in the application will feature video clips of the multiple stories of women living with HIV infection, HIV support group leaders, community leaders, and health care professionals and a Learn More video of physician discussing cervical cancer.

Arm 3

Control: non-narrative educational materials will be read

Group Type PLACEBO_COMPARATOR

Storytelling narrative videos on tablets

Intervention Type BEHAVIORAL

The storytelling narrative episodes in the application will feature video clips of the multiple stories of women living with HIV infection, HIV support group leaders, community leaders, and health care professionals and a Learn More video of physician discussing cervical cancer.

Interventions

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Storytelling narrative videos on tablets

The storytelling narrative episodes in the application will feature video clips of the multiple stories of women living with HIV infection, HIV support group leaders, community leaders, and health care professionals and a Learn More video of physician discussing cervical cancer.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

Women who:

1. are confirmed HIV positive based on medical records
2. are women living with HIV infection support group members
3. are ages 20-50 years
4. are no prior cervical cancer screening
5. are no history of invasive cervical cancer
6. are willingness to participate in the study

Exclusion Criteria

1. are not able to speak Chichewa or English
2. self-report currently receiving treatment of a serious mental illness (e.g., schizophrenia and bipolar disorder)
Minimum Eligible Age

20 Years

Maximum Eligible Age

50 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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University of Massachusetts, Boston

OTHER

Sponsor Role lead

Responsible Party

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Haeok Lee

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Haeok Lee, PhD

Role: PRINCIPAL_INVESTIGATOR

University of Massachusetts, Boston

Locations

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Community organization

Lilongwe, , Malawi

Site Status

Countries

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Malawi

Other Identifiers

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2019250

Identifier Type: -

Identifier Source: org_study_id

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