Assessment of Nutritional Status in Systemic Sclerosis

NCT ID: NCT04301596

Last Updated: 2023-05-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-06-12

Study Completion Date

2024-10-12

Brief Summary

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The main theme of the cohort of systemic sclerosis (SSc) patients is the determination of nutritional status, its evolution and the evaluation of its management in patients with scleroderma.

The main objectives are :

* To determine the incidence of malnutrition and its main determinants (disease characteristics, severity, eating habits, physical activity) in patients with scleroderma.
* For patients with undernutrition at inclusion or at 18 months follow-up:

evaluate the impact of a standardized nutritional intervention (dietary advice, oral supplements, artificial, enteral or parenteral nutrition) on nutritional and disease parameters.

Follow-up visits will take place every 6 months for 2 years. (M6, M12, M18 et M24).

During each visit: a clinical examination, with anthropometric measurements, a 3-day dietary survey and a blood sample (10 ml), completion a multiple-choice of quality of life and physical activity evaluation.

Paraclinical evaluation : echocardiography, lung function tests, screening for osteoporosis (M6 and M18).

If undernutrition is detected during a follow-up visit, the subject will be referred to a specialized service.

Detailed Description

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Conditions

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Systemic Sclerosis

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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SSc patients

Collection of data

Intervention Type OTHER

different set of data will be collected over a 6 months period

Interventions

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Collection of data

different set of data will be collected over a 6 months period

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* All SSc patients aged 18 or more
* Patient followed at the Montpellier University Hospital
* Patients must fulfil the American College of Rheumatology (ACR) and European League Against Rheumatism (EULAR) 2013 criteria for SSc.
* Health insurance (affiliation to social security)
* Collection of non-opposition to participate in the study

Exclusion Criteria

* Patient under the protection of justice curatorship / guardianship;
* Patients who have already planned to move out of the region in the next two years, making the follow-up impossible.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Montpellier

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Alexandre MARIA

Role: PRINCIPAL_INVESTIGATOR

Montpellier University Hospital

Locations

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Montpellier University Hospital

Montpellier, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Alexandre MARIA, MD, PhD

Role: CONTACT

+33467337332

Philippe GUILPAIN

Role: CONTACT

Facility Contacts

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Alexandre MARIA

Role: primary

Other Identifiers

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UF7840

Identifier Type: OTHER

Identifier Source: secondary_id

RECHMPL19_0409

Identifier Type: -

Identifier Source: org_study_id

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