Supermicrosurgical LVA for Lymphedema Treatment

NCT ID: NCT04285762

Last Updated: 2020-02-26

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 100 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2018-11-01
• Study Completion Date: 2019-12-31

Brief Summary

LVA orientations such as lymphaticovenous end-to-end (LVEEA), end-to-side (LVESA), and side-to-end (LVSEA) are commonly performed. Each orientation has its own advantages and disadvantages. The key factors affecting the type of anastomotic orientation are the sizes of the LVs and the RVs, and the relative distance between them. Most published literatures have focused on LVSEA2-9, which is considered to be the most efficient. With one anastomosis in LVSEA, the RV is able to drain both the antegrade and retrograde lymphatic flow. Nevertheless, how to determine the anastomotic orientation has remained ambiguous. In this study, we aimed to establish the basis of selecting the proper anastomotic orientation, based on the size and comparative size discrepancy between LV and RV. To the best of our knowledge, this is the first report to focus on this subject.

Conditions

Lymphedema

Study Design

• Observational Model Type: CASE_CONTROL
• Study Time Perspective: RETROSPECTIVE

Study Groups

Patients underwent supermicrosurgical LVA

Patients underwent supermicrosurgical LVA by a single surgeon from March 2016 to October 2018.

LVEEA

Intervention Type: OTHER

lymphaticovenous end-to-end

LVESA

Intervention Type: OTHER

lymphaticovenous end-to-side

LVSEA

Intervention Type: OTHER

lymphaticovenous side-to-end

Interventions

LVEEA

lymphaticovenous end-to-end

Intervention Type: OTHER

LVESA

lymphaticovenous end-to-side

Intervention Type: OTHER

LVSEA

lymphaticovenous side-to-end

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• lymphedematous lower limbs (International Society of Lymphology stage I-III) between March 2016 to October 2018 were included

Exclusion Criteria

• Patients whose data were missing will be excluded.

• Minimum Eligible Age: 20 Years
• Maximum Eligible Age: 100 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Chang Gung Memorial Hospital

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Locations

Kaohsiung Chang Gung Memorial Hospital

Kaohsiung City, , Taiwan

Countries

Taiwan

Other Identifiers

201801774B0

Identifier Type: -

Identifier Source: org_study_id