Prolactin Hormone in Rheumatoid Arthritis Patients With Periodontitis

NCT ID: NCT04279691

Last Updated: 2020-02-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

30 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-03-31

Study Completion Date

2020-04-30

Brief Summary

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In this study we will assess the presence of prolactin hormone in the gingival crevicular fluid , and synovial fluid of patient with rheumatoid arthritis and periodontitis

Detailed Description

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Conditions

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Rheumatoid Arthritis Periodontitis

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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periodontitis and rheumatoid arthritis

group 1: patiernts with periodontitis and rheumatoid arthritis. only

No interventions assigned to this group

periodontitis

group 2: patiernts with periodontitis

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* for first group patients with active rheumatoid arthritis with periodontitis.
* second group , patients with periodontitis and otherwise systemically healthy
* third group, systemically and periodontallly healthy subjects

Exclusion Criteria

* smokers,
* pregnant or lactating females
* patients taking medications the affects levels of prolactin hormone.
* no periodontal treatment in the past six months
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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October University for Modern Sciences and Arts

OTHER

Sponsor Role lead

Responsible Party

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Naglaa Elwakeel

professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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Naglaa El-Wakeel

Role: CONTACT

01001757761

References

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El-Wakeel NM, Shalaby ZF, Abdulmaguid RF, Elhamed SSA, Shaker O. Local gingival crevicular fluid, synovial fluid, and circulating levels of prolactin hormone in patients with moderately active rheumatoid arthritis and stage III and IV periodontitis before and after non-surgical periodontal treatment-a controlled trial. Clin Oral Investig. 2023 Jun;27(6):2813-2821. doi: 10.1007/s00784-023-04867-w. Epub 2023 Jan 31.

Reference Type DERIVED
PMID: 36717425 (View on PubMed)

Other Identifiers

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ETH14

Identifier Type: -

Identifier Source: org_study_id

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