Assessing Health Related Quality of Life in Hypersensitivity Pneumonitis

NCT ID: NCT04273867

Last Updated: 2023-07-27

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 60 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2020-07-10
• Study Completion Date: 2023-02-22

Brief Summary

The objective of this study is to administer and validate a disease specific health related quality of life (HRQOL) survey for patients with Chronic Hypersensitivity Pneumonitis (CHP).

Detailed Description

The objective of this study is to administer and validate a disease-specific health related quality of life (HRQOL) survey for patients with Chronic Hypersensitivity Pneumonitis (CHP). The survey items have been developed and revised from prior qualitative research with CHP patients. Potential participants will be recruited from WCMC, the Pulmonary Fibrosis Foundation (PFF) Registry and outside physician referral for the study. Participants will be asked to sign informed consent. At the initial visit participants will be asked to complete the survey and two additional PROs needed for concurrent validity testing. Participants will then be asked to complete the HRQOL survey under study a second time 2 weeks after the initial visit for test-re-test reliability testing. Pulmonary function testing and six minute walk test results will be collected. Pertinent demographic and clinical information will be collected from the patients and their medical records or registry data (if a PFF Registry participant). All information will be entered into a REDCap database for secure data management and storage. Psychometric testing will be performed on the overall survey instrument and the individual items in order to test validity and reliability. The goal is that the survey developed will be a reliable and valid measurement tool for use in both clinical practice and research settings.

Conditions

Hypersensitivity Pneumonitis; Chronic Hypersensitivity Pneumonitis; Interstitial Lung Disease; Extrinsic Allergic Alveolitis; Health-related Quality of Life

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Study Groups

Chronic Hypersensitivity Pneumonitis Patients

Chronic Hypersensitivity Pneumonitis Health Related Quality of Life Survey Instrument

Intervention Type: OTHER

This survey has been developed and revised from prior qualitative research with CHP patients and will be used to better evaluate disease status and quality of life with CHP.

Interventions

Chronic Hypersensitivity Pneumonitis Health Related Quality of Life Survey Instrument

This survey has been developed and revised from prior qualitative research with CHP patients and will be used to better evaluate disease status and quality of life with CHP.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

1. 18 years old or older

2. Understand and sign the informed consent document

3. Documented diagnosis of HP made and confirmed at an ILD center via expert consensus or in multidisciplinary discussion

a. Diagnosis based upon a minimum of a medical history, physical examination, pulmonary function testing, and computerized tomography (CT) scan. Pathology will be reviewed if available but is not required.

4. HP must be the primary pulmonary disease

5. Anticipated ability to complete follow up survey within 2 weeks of initial survey completion

6. Participants recruited from the PFF registry must have agreed to be contacted for ancillary research studies.

Exclusion Criteria

1. Non-English Speaking (Patient must be able to speak and read English fluently but it does not have to be their primary language)

2. Inability to complete questionnaire due to cognitive impairment

3. Patients who have not been seen by or communicated with their provider in over 2 years

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Pulmonary Fibrosis Foundation

OTHER

Sponsor Role: collaborator

Weill Medical College of Cornell University

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Kerri I Aronson, MD

Role: PRINCIPAL_INVESTIGATOR

Weill Medical College of Cornell University

Locations

Weill Cornell Medicine

New York, New York, United States

Countries

United States

Other Identifiers

19-05020233

Identifier Type: -

Identifier Source: org_study_id