Epidemiologic and Clinical Characteristics of Optic Neuritis in China
NCT ID: NCT04257734
Last Updated: 2021-01-20
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
1000 participants
OBSERVATIONAL
2020-05-01
2021-06-30
Brief Summary
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Detailed Description
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Primary outcomes:
* To dig out the different visual acuity (VA, LogMAR) prognosis among the three groups;
* To calculate the annual relapse rate (ARR) differences among the three groups (relapse times in all the follow-up time in each group/ follow-up time (years) in all in each group).
Secondary outcomes:
* Other epidemiological and clinical characteristics of optic neuritis patients will be analyzed among the three groups;
* Orbital or Brain MRI is required in this study, which could avoid the misdiagnosis. We will collect and analyze these MRI data too (including the optic nerve lesions in T2 weight images and T1 enhanced MRI);
* Results of optical coherence tomography (OCT) (including peripapillary retinal nerve fiber layer, macular thickness ,and ganglion cell and inner plexiform layer complex) at different time point are also needed in this study. However, OCT is not necessarily required;
* Visual fields at different time points are also encouraged to provide if they are available.
Conditions
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Study Design
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CASE_ONLY
RETROSPECTIVE
Study Groups
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optic neuritis
Aquaporin 4 antibody seropositive optic neuritis patients, Myelin oligodendrocyte glycoprotein antibody seropositive optic neuritis patients, and double antibodies seronegative optic neuritis patients
observation
different serum antibodies status
Interventions
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observation
different serum antibodies status
Eligibility Criteria
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Inclusion Criteria
2. The patients' medical records were complete
Exclusion Criteria
2. Incomplete medical records
ALL
No
Sponsors
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Peking University Health Science Center
OTHER
Chinese PLA General Hospital
OTHER
Responsible Party
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Wei Shihui
Professor
Principal Investigators
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Shihui Wei, M.D
Role: STUDY_CHAIR
Ophthalmology, the Chinese PLA General Hospital
Locations
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Chinese PLA General Hospital
Beijing, Beijing Municipality, China
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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CONSG1
Identifier Type: -
Identifier Source: org_study_id
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