Study of Venous Thromboembolism Risk Profiles and Prophylaxis in Neurosurgical Inpatients

NCT ID: NCT04257305

Last Updated: 2020-02-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

9010 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-06-01

Study Completion Date

2019-12-31

Brief Summary

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Venous thromboembolism (VTE), comprising deep venous thrombosis (DVT), pulmonary embolism (PE), or both, is a life-threatening complication in postoperative patients. VTE has been estimated an incidence ranged from 79 per 100000 to 269 per 100000 population1. The incidence of VTE rises up to 3.0% in average among all postoperative neurosurgical patients in recent studies, but the number varies in a large range according to primary diseases. This cross-sectional study was aimed to investigate the incidence, associated risk factors, prophylaxis, treatment, and outcomes of VTE in a large clinical neurosurgery center in China.

Detailed Description

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Venous thromboembolism (VTE), comprising deep venous thrombosis (DVT), pulmonary embolism (PE), or both, is a life-threatening complication in postoperative patients. This cross-sectional study was aimed to investigate the incidence, associated risk factors, prophylaxis, treatment, and outcomes of VTE in a large clinical neurosurgery center in China. 9010 patients underwent neurosurgery procedure were included. Distribution of age, sex, whether received PICC during perioperative period, and some special primary diseases are significantly different between VTE and non-VTE patients. Student's test and chi-square test were performed for analyses. We investigated VTE incidence, risk factors, prophylaxes, treatment and outcomes in postoperative neurosurgical patients, and summarized the VTE susceptible population of the patients, providing a VTE patient profile for neurosurgeons to concern.

Conditions

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Venous Thromboembolism

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Eligibility Criteria

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Inclusion Criteria

Neurosurgical Inpatients. Underwent neurosurgery procedure.

Exclusion Criteria

Acute or chronic respiratory failure. Acute myocardial infarction or other serious heart diseases.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Huashan Hospital

OTHER

Sponsor Role lead

Responsible Party

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Shengqing Li

Chief Physician,Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Shengqing Li, PhD

Role: PRINCIPAL_INVESTIGATOR

Huashan Hospital

Locations

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Huashan hospital,Fudan university

Shanghai, Shanghai Municipality, China

Site Status

Countries

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China

Other Identifiers

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KY2016-396

Identifier Type: -

Identifier Source: org_study_id

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