Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
150 participants
OBSERVATIONAL
2001-01-01
2019-12-31
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
RETROSPECTIVE
Study Groups
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Water load test
Patients experiencing a syndrome of inappropriate antidiuresis who had an acute water load test
Acute water load test
The acute water load test consists in administering orally 20 mL/kg (of body weight) of water (ingested in less than 30 min) and then follow (during 4 to 6 hours) blood and urine parameters.
Control group
Patients who had an acute water load test and who did not experience any water homeostasis anomalies
Acute water load test
The acute water load test consists in administering orally 20 mL/kg (of body weight) of water (ingested in less than 30 min) and then follow (during 4 to 6 hours) blood and urine parameters.
Interventions
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Acute water load test
The acute water load test consists in administering orally 20 mL/kg (of body weight) of water (ingested in less than 30 min) and then follow (during 4 to 6 hours) blood and urine parameters.
Eligibility Criteria
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Inclusion Criteria
* affiliated to a social insurance system
* water load test performed at the Renal and Metabolic Diseases Unit of the European George Pompidou Hospital, AP-HP, Paris, France
* between 01/01/2001 and 12/31/2019
Exclusion Criteria
* hyponatremia due to a tea and toast syndrome and/or a beer potomania
* hyponatremia due to a high (or normal) osmolality related to diabetes mellitus, hyperproteinemia and/or intoxication
* chronic kidney disease with an estimated glomerular filtration rate (eGFR) by the MDRD formula \<60 mL/min/1.73m2
* hyponatremia related to thiazides
* hyponatremia related to an hypovolemic status
* syndrome of inappropriate antidiuresis related to an endocrine disorder (such as hypothyroidism or adrenal insufficiency)
18 Years
ALL
No
Sponsors
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European Georges Pompidou Hospital
OTHER
Responsible Party
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Jean-philippe Bertocchio, MD, PhD
Principal Investigator
Principal Investigators
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Jean-Philippe Bertocchio, MD, PhD
Role: PRINCIPAL_INVESTIGATOR
Assistance Publique - Hôpitaux de Paris
Locations
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European Georges Pompidou Hospital, APHP
Paris, , France
Countries
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Other Identifiers
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WATERLINE
Identifier Type: -
Identifier Source: org_study_id
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