Diagnostic Value of D-dimer/Fibrinogen Ratio in Patients With Acute Aortic Dissection
NCT ID: NCT04251247
Last Updated: 2024-03-15
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
RECRUITING
159 participants
OBSERVATIONAL
2020-03-01
2025-01-31
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Aortic Dissection Detection Risk Score Plus D-dimer in Suspected Acute Aortic Dissection
NCT02086136
Integrated Diagnostic Algorithm for Acute Aortic Syndromes
NCT04430400
Potential Diagnostic Biomarkers for Aortic Dissection in the Emergency Department
NCT06065306
Blood Biomarker Discovery by Raman Spectroscopy in Acute Aortic Dissection
NCT05206032
Quick Recognition of Aortic Dissection
NCT05699395
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
CASE_CONTROL
PROSPECTIVE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Acute aortic dissection
Patients with a diagnosis of acute aortic dissection.
D-dimer/fibrinogen ratio
The ratio of D-dimer (ng/ml) to fibrinogen (mg/dl)
Acute pulmonary embolism
Patients with a diagnosis of acute pulmonary embolism
D-dimer/fibrinogen ratio
The ratio of D-dimer (ng/ml) to fibrinogen (mg/dl)
Non-cardiac chest pain
Patients with non-cardiac chest pain
D-dimer/fibrinogen ratio
The ratio of D-dimer (ng/ml) to fibrinogen (mg/dl)
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
D-dimer/fibrinogen ratio
The ratio of D-dimer (ng/ml) to fibrinogen (mg/dl)
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Diagnosis of acute pulmonary embolism
* Diagnosis of non-cardiac chest pain
Exclusion Criteria
* Participants who do not give consent for enrollment
18 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Dr. Lutfi Kirdar Kartal Training and Research Hospital
OTHER_GOV
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Ahmet Can Topcu
Director of Department of Cardiovascular Surgery
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital
Istanbul, , Turkey (Türkiye)
Kartal Dr. Lutfi Kirdar Training and Research Hospital
Istanbul, , Turkey (Türkiye)
Countries
Review the countries where the study has at least one active or historical site.
Central Contacts
Reach out to these primary contacts for questions about participation or study logistics.
Facility Contacts
Find local site contact details for specific facilities participating in the trial.
References
Explore related publications, articles, or registry entries linked to this study.
Hajsadeghi S, Kerman SR, Khojandi M, Vaferi H, Ramezani R, Jourshari NM, Mousavi SA, Pouraliakbar H. Accuracy of D-dimer:fibrinogen ratio to diagnose pulmonary thromboembolism in patients admitted to intensive care units. Cardiovasc J Afr. 2012 Sep;23(8):446-56. doi: 10.5830/CVJA-2012-041.
Kara H, Bayir A, Degirmenci S, Kayis SA, Akinci M, Ak A, Celik B, Dogru A, Ozturk B. D-dimer and D-dimer/fibrinogen ratio in predicting pulmonary embolism in patients evaluated in a hospital emergency department. Acta Clin Belg. 2014 Aug;69(4):240-5. doi: 10.1179/2295333714Y.0000000029.
Guan XL, Wang XL, Liu YY, Lan F, Gong M, Li HY, Liu O, Jiang WJ, Liu YM, Zhu JM, Sun LZ, Zhang HJ. Changes in the Hemostatic System of Patients With Acute Aortic Dissection Undergoing Aortic Arch Surgery. Ann Thorac Surg. 2016 Mar;101(3):945-51. doi: 10.1016/j.athoracsur.2015.08.047. Epub 2015 Oct 23.
Eggebrecht H, Naber CK, Bruch C, Kroger K, von Birgelen C, Schmermund A, Wichert M, Bartel T, Mann K, Erbel R. Value of plasma fibrin D-dimers for detection of acute aortic dissection. J Am Coll Cardiol. 2004 Aug 18;44(4):804-9. doi: 10.1016/j.jacc.2004.04.053.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
2020/514/169/B
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.