Taste Function and Eating Habits in Polycystic Ovary Syndrome

NCT ID: NCT04238078

Last Updated: 2021-06-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

80 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-01-15

Study Completion Date

2020-07-15

Brief Summary

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This study evaluates taste function and eating habits in patients with PCOS compared to healthy women and before and after oral contraceptive use.

Detailed Description

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The objective of this study is to investigate the taste function and eating habits in patients with PCOS in comparison with healthy women at baseline and after routine use of an oral contraceptive (2mg ethinylestradiol and 0.03mg dienogest) along with general lifestyle advice for three months.

Patients with diagnosis of PCOS (Rotterdam criteria) will be recruited from Hacettepe University outpatient clinics. Along with clinical, hormonal and biochemical evaluation, taste function and eating habit tests will be performed at baseline both in patients and healthy volunteers. These tests will be repeated in women with PCOS after 3 months of oral contraceptive use.

Conditions

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Polycystic Ovary Syndrome

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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Polycystic ovary syndrome

Women with PCOS diagnosed according to Rotterdam criteria

Contraceptive

Intervention Type DRUG

Oral contraceptive pill

Healthy control

Healthy women without any feature of ovulatory dysfunction or androgen excess

No interventions assigned to this group

Interventions

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Contraceptive

Oral contraceptive pill

Intervention Type DRUG

Other Intervention Names

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birth control pill

Eligibility Criteria

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Inclusion Criteria

* Women diagnosed with PCOS (Rotterdam criteria) who will receive oral contraceptive pill for long-term management

Exclusion Criteria

* Any systemic illness
* Any other medication use
* Age\<18 or \>35 years
* Pregnant or nursing
* Untreated hypothyroidism or hyperthyroidism
* Known rhinoplasty or nasal surgery
* Known defect in smell or taste function
* Being active smoker.
Minimum Eligible Age

18 Years

Maximum Eligible Age

35 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Hacettepe University

OTHER

Sponsor Role lead

Responsible Party

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Okan Bulent Yildiz

Professor of Medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Bulent Yildiz

Role: PRINCIPAL_INVESTIGATOR

Hacettepe University

Locations

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Hacettepe University School of Medicine

Ankara, , Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Simchen U, Koebnick C, Hoyer S, Issanchou S, Zunft HJ. Odour and taste sensitivity is associated with body weight and extent of misreporting of body weight. Eur J Clin Nutr. 2006 Jun;60(6):698-705. doi: 10.1038/sj.ejcn.1602371. Epub 2006 Jan 25.

Reference Type RESULT
PMID: 16435003 (View on PubMed)

Wolf A, Varga L, Wittibschlager L, Renner B, Mueller CA. A self-administered test of taste function using "Taste Strips". Int Forum Allergy Rhinol. 2016 Apr;6(4):362-6. doi: 10.1002/alr.21681. Epub 2015 Dec 3.

Reference Type RESULT
PMID: 26633243 (View on PubMed)

Other Identifiers

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17697

Identifier Type: -

Identifier Source: org_study_id

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