Women With Polycystic Ovary Syndrome Have Increased Plasma Chitotriosidase Activity

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

78 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-01-31

Study Completion Date

2010-12-31

Brief Summary

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In the present study, serum chitotriosidase activity and its relationship with insulin resistance were determined in patients with Polycystic Ovary Syndrome (PCOS).

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Detailed Description

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ChT activity is increased in patients with PCOS in concordance with insulin resistance. These findings may reflect the pronounced risk for metabolic syndrome and atherosclerotic diseases in this particular patient group.

Conditions

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Polycystic Ovary Syndrome

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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PCOS patients

No interventions assigned to this group

PCOS patients and healthy controls

There are two groups in this study. One group is PCOS patients and other group is healthy controls.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Absence of significant abnormalities on physical examination except hirsutism
* no lipid lowering, hypoglycemic, antihypertensive or hormone replacement therapy
* normal thyroid function and prolactin level
* absence of history or evidence of metabolic, cardiovascular, respiratory or hepatic disease