Short-term Effect of Rho-kinase Inhibitor on Retinal Circulation

NCT ID: NCT04234932

Last Updated: 2020-04-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

EARLY_PHASE1

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-01-06

Study Completion Date

2021-01-31

Brief Summary

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Investigate changes in optical coherence tomography angiography of the optic nerve and macula following topical instillation of commercial preparations of netarsudil 0.02% ophthalmic solution.

Detailed Description

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Conditions

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Glaucoma, Open-Angle

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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Netarsudil alone

Topical application of netarsudil 0.02%

Group Type EXPERIMENTAL

Netarsudil Ophthalmic

Intervention Type DRUG

Topical instillation of commercial preparations of netarsudil 0.02% ophthalmic solution (Rhopressa and Roclatan)

Netarsudil plus latanoprost

Topical application of netarsudil 0.02% with latanoprost 0.005%

Group Type ACTIVE_COMPARATOR

Netarsudil Ophthalmic

Intervention Type DRUG

Topical instillation of commercial preparations of netarsudil 0.02% ophthalmic solution (Rhopressa and Roclatan)

Interventions

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Netarsudil Ophthalmic

Topical instillation of commercial preparations of netarsudil 0.02% ophthalmic solution (Rhopressa and Roclatan)

Intervention Type DRUG

Other Intervention Names

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Latanoprost Ophthalmic

Eligibility Criteria

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Inclusion Criteria

* Normal ocular health

Exclusion Criteria

* Females who are or may be pregnant or who are nursing
* Uncontrolled hypertension
* Allergy to netarsudil or latanoprost
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of the Incarnate Word

OTHER

Sponsor Role lead

Responsible Party

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Richard Trevino, OD, FAAO

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University of the Incarnate Word

San Antonio, Texas, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Mary Jo Bilicek

Role: CONTACT

210-805-3565

Facility Contacts

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Ana C Hagendorf, PhD

Role: primary

210-805-3036

Other Identifiers

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19-12-005

Identifier Type: -

Identifier Source: org_study_id

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