Diameters and Wall-to-lumen Ratio of Retinal Arterioles in Patients With Retinal Vein Occlusion.

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-06-30

Study Completion Date

2013-01-31

Brief Summary

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to evaluate the wall-to-lumen ratio (WLR) of retinal arterioles in hypertensive patients with retinal vein occlusion (RVO) before and after dexamethasone intravitreal implant 0.7 mg (DEX) compared to a matched control group of normal eyes in non-hypertensive subjects.

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Detailed Description

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Conditions

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Hypertensive Patients With Retinal Vein Occlusion

Study Design

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Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Dexamethasone Intravitreal Implant

Group Type ACTIVE_COMPARATOR

Dexamethasone Intravitreal Implant (Ozuredex)

Intervention Type DEVICE

Interventions

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Dexamethasone Intravitreal Implant (Ozuredex)

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* ability to provide written informed consent and comply with study assessments for the full duration of the study;
* age \> 20 years;
* decreased visual acuity as a result of clinically detectable ME associated with either CRVO or BRVO;
* the duration of macular edema was required to be between 4 and 24 weeks for both CRVO and BRVO;
* retinal thickness in the central subfield (as measured using optical coherence tomography) had to be \> 350 µm in the study eye.

Minimum Eligible Age

20 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No