Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
40 participants
INTERVENTIONAL
2013-01-03
2015-12-30
Brief Summary
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Within a randomized double-blind placebo-controlled trial, the investigators tested the hypotheses 1) that a 4-week protein-rich diet induces a latent tissue acidosis and 2) an alkaline supplement can compensate this. Acid-base balance and important metabolic parameters were determined before and after 4 weeks of supplementation by peripheral blood samples, indirect calorimetry and muscle microdialysis before and after a protein-rich test meal.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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Basica
4-week dietary supplementation with an alkaline salt (Basica)
alkaline salt mixture
blood and tissue alkalinisation
Placebo
4-week dietary supplementation with a placebo
placebo
no blood and tissue alkalinisation
Interventions
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alkaline salt mixture
blood and tissue alkalinisation
placebo
no blood and tissue alkalinisation
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Body mass index 20.0 - 29.9 kg/m2
* normal daily diet composition: 45-50, 35-40, and 15 E% from carbs, fats and proteins, respectively
Exclusion Criteria
* intake of antacidic drugs
* vegetarians, vegans
* intake of any nutritional supplements
* any cardiovascular, pulmonary, endocrine or metabolic diseases
* any drug abuse
* intake of any anticoagulant drugs
60 Years
70 Years
ALL
No
Sponsors
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Charite University, Berlin, Germany
OTHER
Responsible Party
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Michael Boschmann
Principal Investigator
Other Identifiers
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BASICA
Identifier Type: -
Identifier Source: org_study_id
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