Clinical Effect of Chlorhexidine Mouthwash After Periodontal Surgery

NCT ID: NCT04223076

Last Updated: 2020-01-13

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE4

Total Enrollment

31 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-03-20

Study Completion Date

2020-12-30

Brief Summary

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Chlorhexidine is the gold standard of dental plaque prevention. Recent research have demonstrated that 0.2% Chlorhexidine solutions are more effective than 0.12% and 0.06% Chlorhexidine solutions. Several 0.2% solutions are available on the market. This study aimed to compare effectiveness of two commercially available 0.2% chlorhexidine mouthwashes. Patients, that after initial periodontal therapy, had a need for two periodontal surgeries, will be invited to join. After one surgical session, the patient will receive one 0.2% chlorhexidine solution, and after the next surgical session the patient will receive the other 0.2% chlorhexidine solution. Plaque and gingivitis will be recorded, as well as side effects.

Detailed Description

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Conditions

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Periodontal Diseases Periodontitis Dental Plaque

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Intra individual cross-over, double intervention
Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

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Chlorhexidine 0.2% mouthwash control

Chlorhexidine 0.2%, Corsodyl Intervention rinsing 60 sec twice daily

Group Type EXPERIMENTAL

Chlorhexidine 0.2%, Corsodyl

Intervention Type DRUG

Comparison of Corsodyl and Curasept

Chlorhexidine 0.2% mouthwash with an Anti Discoloring System

Chlorhexidine 0.2%, Curasept Intervention rinsing 60 sec twice daily

Group Type EXPERIMENTAL

Chlorhexidine 0.2%, Curasept

Intervention Type DRUG

Chlorhexidine 0.2% mouthwash with an Anti Discoloring System (ADS)

Interventions

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Chlorhexidine 0.2%, Corsodyl

Comparison of Corsodyl and Curasept

Intervention Type DRUG

Chlorhexidine 0.2%, Curasept

Chlorhexidine 0.2% mouthwash with an Anti Discoloring System (ADS)

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

Periodontitis, stage III and IV

Exclusion Criteria

Uncontrolled diabetes Systemic conditions associated with excessive bleeding Uncontrolled hypertension
Minimum Eligible Age

18 Years

Maximum Eligible Age

90 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Oslo

OTHER

Sponsor Role lead

Responsible Party

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Erik Mauland

DDS

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Anne Merete Aass, Professor

Role: STUDY_CHAIR

University of Oslo

Locations

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Erik Mauland

Oslo, , Norway

Site Status RECRUITING

Countries

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Norway

Central Contacts

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Erik Mauland, DDS

Role: CONTACT

004747636914

Hans Preus, Professor

Role: CONTACT

Facility Contacts

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Erik Mauland

Role: primary

Other Identifiers

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2020/121314

Identifier Type: -

Identifier Source: org_study_id

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