A Prospective Cohort of Pulmonary Ground Glass Nodules Patients With Family History.
NCT ID: NCT04220268
Last Updated: 2020-01-07
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
600 participants
OBSERVATIONAL
2020-01-05
2022-01-31
Brief Summary
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Detailed Description
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This prospective cohort study, with both a cross-sectional and a longitudinal part, will include patients with pulmonary ground glass nodule, which were proven malignant disease.
All participants will be asked to complete questionnaire to build the clinical database of GGN patients with detailed family history. Furthermore, blood and surgical tumor samples will be collected as a specific biobank. And the blood samples of other family members of participants will be collected, with their consent and knowledge.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Participants
All the patients with proved malignant ground glass nodule will be enrolled.
No interventions assigned to this group
Eligibility Criteria
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Inclusion Criteria
2. patients with pulmonary ground glass nodule.
3. pathological proved early stage lung cancer.
ALL
No
Sponsors
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Guangdong Provincial People's Hospital
OTHER
Responsible Party
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Wen-zhao ZHONG
Porfessor
Principal Investigators
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Wenzhao Zhong, Ph。D
Role: PRINCIPAL_INVESTIGATOR
Guangdong Provincial People's Hospital
Locations
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Guangdong Provincial People's Hospital
Guangzhou, Guangdong, China
Countries
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Central Contacts
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Facility Contacts
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References
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Dai J, Lv J, Zhu M, Wang Y, Qin N, Ma H, He YQ, Zhang R, Tan W, Fan J, Wang T, Zheng H, Sun Q, Wang L, Huang M, Ge Z, Yu C, Guo Y, Wang TM, Wang J, Xu L, Wu W, Chen L, Bian Z, Walters R, Millwood IY, Li XZ, Wang X, Hung RJ, Christiani DC, Chen H, Wang M, Wang C, Jiang Y, Chen K, Chen Z, Jin G, Wu T, Lin D, Hu Z, Amos CI, Wu C, Wei Q, Jia WH, Li L, Shen H. Identification of risk loci and a polygenic risk score for lung cancer: a large-scale prospective cohort study in Chinese populations. Lancet Respir Med. 2019 Oct;7(10):881-891. doi: 10.1016/S2213-2600(19)30144-4. Epub 2019 Jul 17.
Other Identifiers
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GGN-family
Identifier Type: -
Identifier Source: org_study_id
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