Optimizing the Management of Postpartum Urinary Retention

NCT ID: NCT04187365

Last Updated: 2022-04-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

TERMINATED

Clinical Phase

NA

Total Enrollment

70 participants

Study Classification

INTERVENTIONAL

Study Start Date

2019-11-22

Study Completion Date

2022-02-27

Brief Summary

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A study aimed at characterizing the comparing duration of catheterization for treatment of postpartum urinary retention (PUR) and characterizing short and long-term pelvic floor symptoms in women who have PUR.

Detailed Description

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The purpose of the study is to compare clinical outcomes of women with bladder distension injuries due to postpartum urinary retention (PUR) who have varying duration of catheterization for initial treatment of postpartum urinary retention.

Hypotheses

1. Longer duration of therapeutic catheterization will be associated with resolution of postpartum voiding dysfunction in women who sustain severe bladder distension injuries due to postpartum urinary retention.

Definition of resolution of postpartum voiding dysfunction:

A. A post void residual volume of less than half of initial instilled volume on the first retrograde voiding trial, AND B. No need for re-treatment for urinary retention within 1 week
2. The incidence of postpartum urinary retention (PUR) will vary by route of delivery, with operative vaginal delivery having the highest incidence.
3. Risk factors for PUR will be related to intrapartum and delivery conditions

Conditions

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Urinary Retention

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SINGLE_GROUP

In Arm 2, women with severe postpartum urinary retention will be randomized to 3 or 7 days of foley catheter.
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

No masking.

Study Groups

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GROUP 1 (NonSevere PUR and women without PUR)

Women in GROUP 1 will be prospectively observed to characterize their clinical outcomes.

Group Type NO_INTERVENTION

No interventions assigned to this group

GROUP 2 (Severe PUR)

Women in GROUP 2 will be a randomized to either 3 or 7 days of indwelling catheterization.

Group Type EXPERIMENTAL

Duration of Indwelling Catheter

Intervention Type OTHER

Foley catheter

Interventions

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Duration of Indwelling Catheter

Foley catheter

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

1. Age greater than or equal to 18.
2. Vaginal or cesarean delivery at term (37 weeks gestational age or later) of live-born infants.
3. English or Spanish speaking and reading.

Exclusion Criteria

1. Adults unable to consent.
2. Women under the age of 18.
3. Women who are currently pregnant (All women in the study will have already delivered).
4. Prisoners or detained individuals.
5. Women who chronically use a urinary catheter for another medical condition.
6. Women with a neurological disease with bladder manifestations (examples: Cerebrovascular accidents, Multiple sclerosis, Parkinson disease, cerebral palsy).
7. Women with preeclampsia requiring magnesium treatment for seizure prevention.
8. Women with prior PUR
9. Women on anticholinergic medications.
10. Women who are actively being treated for a UTI.
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Northwestern University

OTHER

Sponsor Role lead

Responsible Party

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Sarah Collins

Assistant Professor, Department of Obstetrics & Gynecology

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Sarah Collins, MD

Role: PRINCIPAL_INVESTIGATOR

Northwestern University

Locations

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Northwestern Medicine

Chicago, Illinois, United States

Site Status

Countries

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United States

Other Identifiers

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STU00210382

Identifier Type: -

Identifier Source: org_study_id

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